{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T14:06:27Z","timestamp":1790085987027,"version":"4.0.1"},"reference-count":30,"publisher":"SAGE Publications","issue":"5","license":[{"start":{"date-parts":[[2021,10,18]],"date-time":"2021-10-18T00:00:00Z","timestamp":1634515200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100013058","name":"Jiangsu Provincial Key Research and Development Program","doi-asserted-by":"publisher","award":["BE 2019670"],"award-info":[{"award-number":["BE 2019670"]}],"id":[{"id":"10.13039\/501100013058","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2024,5]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>The etiology of sudden sensorineural hearing loss (SSNHL) remains unknown; inflammation may be one cause. We retrospectively studied SSHNL cases in terms of the inflammatory parameters involved.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We reviewed 169 SSNHL cases. The control group contained 132 patients with vocal cord polyps. The C-reactive protein (CRP) level, CRP\/serum albumin (Alb) ratio, and neutrophil\/lymphocyte ratio (NLR) were compared between the 2 groups. The relationships between these parameters and the time to treatment after SSHNL onset, hearing level, and therapeutic effects were also analyzed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>The CRP level, CRP\/Alb ratio, and NLR were higher in SSNHL patients than in controls, but only the NLR differed significantly between the 2 groups. We found no significant differences between patients with different hearing levels, those evaluated at various times after SSNHL onset, and those with different outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>The NLR is a reliable SSNHL diagnostic marker. The CRP level and CRP\/Alb ratio are not useful indicators.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0145561320960355","type":"journal-article","created":{"date-parts":[[2021,10,19]],"date-time":"2021-10-19T05:45:20Z","timestamp":1634622320000},"page":"313-318","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["The Roles Played by Blood Inflammatory Parameters in Sudden Sensorineural Hearing Loss"],"prefix":"10.1177","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0321-2936","authenticated-orcid":false,"given":"Yan","family":"Guo","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, The First Affiliated Hospital of Soochow University, Suzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jisheng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, The First Affiliated Hospital of Soochow University, Suzhou, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2021,10,18]]},"reference":[{"key":"bibr1-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1177\/000348947708600406"},{"issue":"5","key":"bibr2-0145561320960355","first-page":"2347","volume":"120","author":"Chau JK","year":"2010","journal-title":"Laryngoscope"},{"key":"bibr3-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1177\/1084713811408349"},{"key":"bibr4-0145561320960355","doi-asserted-by":"publisher","DOI":"10.12968\/hmed.2012.73.2.86"},{"key":"bibr5-0145561320960355","doi-asserted-by":"publisher","DOI":"10.3109\/01677063.2011.652266"},{"key":"bibr6-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-012-2294-y"},{"key":"bibr7-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e3182635417"},{"key":"bibr8-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1186\/cc4892"},{"key":"bibr9-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1086\/430382"},{"key":"bibr10-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2018.10.007"},{"key":"bibr11-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31829b57df"},{"key":"bibr12-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2016.06.005"},{"key":"bibr13-0145561320960355","doi-asserted-by":"publisher","DOI":"10.5152\/iao.2017.2780"},{"issue":"99","key":"bibr14-0145561320960355","first-page":"219","volume":"30","author":"Baradaranfar M","year":"2018","journal-title":"Iran J Otorhinolaryngol"},{"key":"bibr15-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1177\/193229681000400326"},{"key":"bibr16-0145561320960355","doi-asserted-by":"publisher","DOI":"10.6061\/clinics\/2016(04)11"},{"key":"bibr17-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-007-0928-0"},{"key":"bibr18-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2009.12.004"},{"key":"bibr19-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1016\/j.tranon.2015.06.006"},{"key":"bibr20-0145561320960355","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.897460"},{"key":"bibr21-0145561320960355","doi-asserted-by":"publisher","DOI":"10.7150\/jca.15401"},{"key":"bibr22-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000012492"},{"key":"bibr23-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijsu.2015.07.681"},{"key":"bibr24-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-30469-8"},{"key":"bibr25-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0193018"},{"key":"bibr26-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2015.08.009"},{"key":"bibr27-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/702807"},{"issue":"3","key":"bibr28-0145561320960355","first-page":"449","volume":"114","author":"Thomas MR","year":"2015","journal-title":"Thromb Haemost"},{"key":"bibr29-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1093\/fampra\/cmw100"},{"key":"bibr30-0145561320960355","doi-asserted-by":"publisher","DOI":"10.1080\/09537104.2016.1240766"}],"container-title":["Ear, Nose &amp; 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