{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,24]],"date-time":"2026-07-24T17:55:13Z","timestamp":1784915713665,"version":"3.55.0"},"reference-count":34,"publisher":"SAGE Publications","issue":"3_suppl","license":[{"start":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T00:00:00Z","timestamp":1607904000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2021,6]]},"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To assess clinical and functional outcomes of a fat graft myringoplasty under local in an office setting.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Design:<\/jats:title>\n                    <jats:p>Prospective case series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Setting:<\/jats:title>\n                    <jats:p>Tertiary care facility.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients:<\/jats:title>\n                    <jats:p>Patients with a tympanic membrane (TM) perforation presenting between December 2005 and June 2019. Inclusion criteria included perforation size &gt;25% of the surface of the pars tensa of the TM, entire perforation margins visualized through a transcanal view, and lack of spontaneous closure at the 6-month follow-up. The exclusion criteria were the presence of cholesteatoma, wet appearance of the mucosa in the tympanic cavity, ear discharge in the 3 months before surgery, or signs of ossicular inconsistency.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Intervention:<\/jats:title>\n                    <jats:p>In-office fat graft myringoplasty technique under local anesthesia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Main outcome Measures:<\/jats:title>\n                    <jats:p>Complete perforation closure rate and audiometric outcomes.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>A total of 121 patients underwent the procedure, of whom 21 had bilateral sequential procedures (total 142 ears). Average age was 51.1 \u00b1 18.4 years (range, 3-78 years). The size of perforation was &lt;25% of TM in 39 (27.5%) ears, 25% to 50% of TM in 49 (34.55%) ears, 50% to 75% of TM in 34 (23.91%) ears, and 75% to 100% of TM in 20 (14.10%) ears. Complete perforation closure was evident in 130 (91.55%) of the 142 ears. Preoperative mean air conduction threshold was 59.3 dB (17-95 dB) and significantly improved into 35.6 dB (10-85 dB; P &lt; .0004) after surgery. Preoperative air\u2013bone gap was 30.2 dB (5-70 dB) and also significantly improved into 10.2 dB (5-65 dB; P &lt; .0001) after surgery.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>In office fat graft myringoplasty, in adult and pediatric patients with variable perforation sizes, is a well-tolerated procedure with very satisfactory clinical results.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0145561320973555","type":"journal-article","created":{"date-parts":[[2020,12,14]],"date-time":"2020-12-14T11:16:24Z","timestamp":1607944584000},"page":"229S-234S","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Long-Term Follow-Up After Fat Graft Myringoplasty: Do Size and Location Matter?"],"prefix":"10.1177","volume":"100","author":[{"given":"Alfonso Rodriguez","family":"Diaz","sequence":"first","affiliation":[{"name":"Hospital Naval de San Carlos, Otorhinolaryngology Department Hospital Naval de San Carlos, San Fernando Cadiz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1670-4235","authenticated-orcid":false,"given":"Carlos O\u2019Connor","family":"Reina","sequence":"additional","affiliation":[{"name":"Othorhinolaryngology Department, Hospital Quironsalud Marbella, Marbella, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillermo","family":"Plaza","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology Department, Hospital Universitario de Fuenlabrada. Universidad Rey Juan Carlos. Hospital Sanitas La Zarzuela. Madrid. Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena Rodriguez","family":"Posadas","sequence":"additional","affiliation":[{"name":"Othorhinolaryngology Department, Hospital Quironsalud Campo de Gibraltar, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco Valdeon","family":"Arevalo","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology Department, Hospital Naval de San Carlos, San Fernando Cadiz, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Teresa Garcia","family":"Iriarte","sequence":"additional","affiliation":[{"name":"Otorhinolaryngology Department, Hospital la Merced Osuna Sevilla, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2020,12,14]]},"reference":[{"key":"bibr1-0145561320973555","first-page":"97","volume-title":"Otologia","author":"Gil Carcedo LM","year":"2004"},{"key":"bibr2-0145561320973555","unstructured":"Suarez C. 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