{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:08:26Z","timestamp":1777561706755,"version":"3.51.4"},"reference-count":16,"publisher":"SAGE Publications","issue":"2_suppl","license":[{"start":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T00:00:00Z","timestamp":1608595200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2021,4]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives:<\/jats:title>\n                    <jats:p>Alteration of smell and taste has been reported in patients with coronavirus disease 2019 (COVID-19). The incidence and clinical-symptomatic manifestation of COVID-19 is different between northern and southern Italy. This study aims to evaluate the onset of alteration of smell and taste in asymptomatic and symptomatic patients in Sicily (extreme south of Italy).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>This prospective cross-sectional study was performed on asymptomatic and symptomatic COVID-19 patients tested for severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) from May 1 to May 15, 2020. A questionnaire was used for evaluating the prevalence of smell and taste disorders in COVID-19 patients before performing nasopharyngeal swab.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>Of the total 292 patients, 242 (83.2%) were negative for SARS-CoV-2 and 50 were positive (16.8%). Twenty-six of the 50 (52%) SARS-CoV-2 positive patients reported smell\/taste disorders. Twenty-eight of the 50 (57.1%) SARS-CoV-2 positive patients were hospitalized (group A), and 22 (42.9%) were nonhospitalized (group B). The mean age in group A and group B was 45.4 \u00b1 13.7 years and 57.0 \u00b1 15.0, respectively ( P = .007). The symptoms reported by hospitalized patients were fever (71.4%), cough (64.2%), fatigue (82.1%), and dyspnea (100%), while in nonhospitalized patients, the most reported symptoms were sore throat (72.7%), rhinorrhea (77.2%), and altered smell (81.8%). Anosmia\/hyposmia reported in group A and group B was 28.5% and 81.8%, respectively ( P = .001).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>These preliminary results indicate that the majority of SARS-Cov-2 positive patients in southern Italy did not require hospitalization and presented with milder symptoms or no symptoms and the alterations in smell and taste occurred.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/0145561320981447","type":"journal-article","created":{"date-parts":[[2020,12,22]],"date-time":"2020-12-22T08:21:00Z","timestamp":1608625260000},"page":"182S-185S","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":17,"title":["Alteration of Smell and Taste in Asymptomatic and Symptomatic COVID-19 Patients in Sicily, Italy"],"prefix":"10.1177","volume":"100","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4512-1378","authenticated-orcid":false,"given":"Maria Rita","family":"Bianco","sequence":"first","affiliation":[{"name":"Otolaryngology, Department of Health Science, University of Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2016-4101","authenticated-orcid":false,"given":"Domenico M.","family":"Modica","sequence":"additional","affiliation":[{"name":"Public Health, Epidemiology and Preventive Medicine, ASP Trapani, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaetano D.","family":"Drago","sequence":"additional","affiliation":[{"name":"Infectious Diseases Unit, Cannizzaro Hospital, Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfio","family":"Azzolina","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Cannizzaro Hospital, Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gianfranco","family":"Mattina","sequence":"additional","affiliation":[{"name":"Public Health, Epidemiology and Preventive Medicine, ASP Trapani, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Massimo","family":"De Natale","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Cannizzaro Hospital, Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Rossi","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Cannizzaro Hospital, Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Amata","sequence":"additional","affiliation":[{"name":"Department of Biomedicine and Internal and Specialistic Medicine (DIBIMIS), University of Palermo, Palermo, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gaspare","family":"Canzoneri","sequence":"additional","affiliation":[{"name":"Public Health, Epidemiology and Preventive Medicine, ASP Trapani, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giovanni","family":"Manganaro","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Cannizzaro Hospital, Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francesco","family":"Di Gregorio","sequence":"additional","affiliation":[{"name":"Public Health, Epidemiology and Preventive Medicine, ASP Trapani, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rosario","family":"Russo","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Cannizzaro Hospital, Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salvatore","family":"Pricoco","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Cannizzaro Hospital, Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vincenzo","family":"Saita","sequence":"additional","affiliation":[{"name":"Otolaryngology Unit, Cannizzaro Hospital, Catania, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5202-4333","authenticated-orcid":false,"given":"Eugenia","family":"Allegra","sequence":"additional","affiliation":[{"name":"Otolaryngology, Department of Health Science, University of Catanzaro, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2020,12,22]]},"reference":[{"key":"bibr1-0145561320981447","unstructured":"https:\/\/www.who.int\/dg\/speeches\/detail\/who-director-general-s-opening-remarks-at-the-media-briefing-on-covid-1911-march-2020"},{"key":"bibr2-0145561320981447","unstructured":"Accessed May 11, 2020. 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