{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:18:21Z","timestamp":1777562301054,"version":"3.51.4"},"reference-count":8,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2021,12,29]],"date-time":"2021-12-29T00:00:00Z","timestamp":1640736000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2024,8]]},"abstract":"<jats:p>Substance abuse is a rare but known cause of sensorineural hearing loss (SNHL). We report a case of acute SNHL in a 28-year-old man following an overdose of methamphetamine and incidental ingestion of fentanyl. On initial encounter, he had moderate-to-severe hearing loss in the right ear and severe-to-profound hearing loss in the left ear in addition to acute kidney injury, liver failure, and lactic acidosis. The patient was treated with a two-week course of high-dose steroids and expressed a subjective improvement in hearing. This case highlights the importance of auditory testing following a drug overdose and is one of the only documented cases of hearing loss following methamphetamine use in recent years. There is a paucity of literature regarding the mechanism causing acute SNHL secondary to methamphetamines. Proposed etiologies include neurotransmitter depletion or reduced cochlear blood flow as possible causes of ototoxicity.<\/jats:p>","DOI":"10.1177\/01455613211069353","type":"journal-article","created":{"date-parts":[[2021,12,29]],"date-time":"2021-12-29T15:25:56Z","timestamp":1640791556000},"page":"NP491-NP493","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Bilateral Sensorineural Hearing Loss in the Setting of Acute Methamphetamine Overdose"],"prefix":"10.1177","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-6211-9723","authenticated-orcid":false,"given":"Jeremy S.","family":"Reich","sequence":"first","affiliation":[{"name":"Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5430-2977","authenticated-orcid":false,"given":"Harleen K.","family":"Sethi","sequence":"additional","affiliation":[{"name":"Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA"},{"name":"Department of Otolaryngology-Head and Neck Surgery, Philadelphia College of Osteopathic Medicine, Philadelphia, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5146-6319","authenticated-orcid":false,"given":"Robert T.","family":"Sataloff","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Drexel University College of Medicine, Philadelphia, Pennsylvania, PA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2021,12,29]]},"reference":[{"key":"bibr1-01455613211069353","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.2000.10400221"},{"key":"bibr2-01455613211069353","doi-asserted-by":"publisher","DOI":"10.1016\/j.jchf.2017.02.017"},{"key":"bibr3-01455613211069353","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000007666"},{"key":"bibr4-01455613211069353","doi-asserted-by":"publisher","DOI":"10.1016\/j.psychres.2018.05.033"},{"key":"bibr5-01455613211069353","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2019.2851"},{"key":"bibr6-01455613211069353","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.2002.10399981"},{"key":"bibr7-01455613211069353","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(94)90528-2"},{"key":"bibr8-01455613211069353","doi-asserted-by":"publisher","DOI":"10.1080\/02791072.2004.10399740"}],"container-title":["Ear, Nose &amp; Throat Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613211069353","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/01455613211069353","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613211069353","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:35:56Z","timestamp":1777401356000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/01455613211069353"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,12,29]]},"references-count":8,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2024,8]]}},"alternative-id":["10.1177\/01455613211069353"],"URL":"https:\/\/doi.org\/10.1177\/01455613211069353","relation":{},"ISSN":["0145-5613","1942-7522"],"issn-type":[{"value":"0145-5613","type":"print"},{"value":"1942-7522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,12,29]]}}}