{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:21:34Z","timestamp":1777562494870,"version":"3.51.4"},"reference-count":10,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T00:00:00Z","timestamp":1648771200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2025,1]]},"abstract":"<jats:sec>\n                    <jats:title>Hypothesis<\/jats:title>\n                    <jats:p>The amount and viscosity of middle ear fluid probably influences the vibration function of the tympanic membrane (TM).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>There has been much research into the mechanisms of hearing loss resulting from middle ear fluid in the previous study. However, further study is required to understand how the middle ear fluid affects the vibration function of the TM.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Tests on a TM in a fresh cadaveric human temporal bone specimen under different simulated conditions were carried out. Saline (1 cSt) and silicone oil (100 cSt, 1 000 cSt, 12 500 cSt) were used to simulate middle ear fluid. The fluid approximately contacted 50% or 100% of TM, which was proportional to the fluid amount. Induced by stimulus signal with frequency domain from 0.25 to 8 kHz, the vibration at 6 points of the TM was measured by laser Doppler vibrometer (LDV), respectively. Data acquisition and processing were accomplished by self-developed software.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>With the increase of the fluid amount, the magnitude of velocity transfer function reduced across all frequencies. The effect of fluid viscosity on the TM vibration varied and reduced in a complicated way when the fluid viscosity changed.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Increasing fluid amount will significantly reduce the TM movement. The effect of fluid viscosity on the TM vibration was nonlinear and related to the fluid amount. The vibration at each point on the TM is frequency-dependent.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/01455613221086023","type":"journal-article","created":{"date-parts":[[2022,4,1]],"date-time":"2022-04-01T10:38:44Z","timestamp":1648809524000},"page":"54-61","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Vibration of Tympanic Membrane Influenced by Middle Ear Fluid"],"prefix":"10.1177","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9718-2415","authenticated-orcid":false,"given":"Lijian","family":"Wang","sequence":"first","affiliation":[{"name":"School of Biomedical Engineering, Capital Medical University, Beijing, China"},{"name":"Department of Clinical Engineering, 2nd Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jie","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China"},{"name":"Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Capital Medical University, Beijing, China"},{"name":"Beijing Engineering Research Center of Audiology Technology, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lifang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Beijing, China"},{"name":"Key Laboratory of Otolaryngology Head and Neck Surgery, Ministry of Education, Capital Medical University, Beijing, China"},{"name":"Beijing Engineering Research Center of Audiology Technology, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xia","family":"Li","sequence":"additional","affiliation":[{"name":"School of Biomedical Engineering, Capital Medical University, Beijing, China"},{"name":"School of Biomedical Engineering, Beijing Key Laboratory of Fundamental Research on Biomechanics in Clinical Application, Capital Medical University, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,4,1]]},"reference":[{"key":"bibr1-01455613221086023","doi-asserted-by":"publisher","DOI":"10.1097\/00129492-200303000-00008"},{"key":"bibr2-01455613221086023","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200103000-00022"},{"key":"bibr3-01455613221086023","doi-asserted-by":"publisher","DOI":"10.1016\/0143-8166(95)00076-3"},{"key":"bibr4-01455613221086023","doi-asserted-by":"publisher","DOI":"10.1016\/j.heares.2004.05.010"},{"key":"bibr5-01455613221086023","doi-asserted-by":"publisher","DOI":"10.1177\/000348948809700311"},{"key":"bibr6-01455613221086023","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-5876(83)80006-8"},{"key":"bibr7-01455613221086023","doi-asserted-by":"publisher","DOI":"10.1288\/00005537-197304000-00015"},{"key":"bibr8-01455613221086023","doi-asserted-by":"publisher","DOI":"10.3109\/00016485809134725"},{"key":"bibr9-01455613221086023","doi-asserted-by":"publisher","DOI":"10.1121\/1.2793699"},{"key":"bibr10-01455613221086023","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0b013e31822e94f3"}],"container-title":["Ear, Nose &amp; Throat Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613221086023","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/01455613221086023","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613221086023","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:36:24Z","timestamp":1777401384000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/01455613221086023"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,1]]},"references-count":10,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1]]}},"alternative-id":["10.1177\/01455613221086023"],"URL":"https:\/\/doi.org\/10.1177\/01455613221086023","relation":{},"ISSN":["0145-5613","1942-7522"],"issn-type":[{"value":"0145-5613","type":"print"},{"value":"1942-7522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,1]]}}}