{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,25]],"date-time":"2026-08-25T13:35:47Z","timestamp":1787664947244,"version":"build-2736575974"},"reference-count":28,"publisher":"SAGE Publications","issue":"12","license":[{"start":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T00:00:00Z","timestamp":1648080000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"name":"Lanzhou Science and Technology Project","award":["2016-3-122"],"award-info":[{"award-number":["2016-3-122"]}]},{"DOI":"10.13039\/501100001809","name":"National Nature Science Foundation of China","doi-asserted-by":"crossref","award":["51501042"],"award-info":[{"award-number":["51501042"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Gansu Province Science and Technology Innovation and Development Special Fund Project","award":["2018ZX-03"],"award-info":[{"award-number":["2018ZX-03"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2024,12]]},"abstract":"<jats:sec>\n                    <jats:title>Purpose<\/jats:title>\n                    <jats:p>The relationship between ankyloglossia and speech is controversial. Our objective in the present study was to determine the most appropriate intervention and optimal timing for infants with speech articulation caused by ankyloglossia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Patients and Methods<\/jats:title>\n                    <jats:p>A total of 341 pediatric patients (aged 2 to 5\u00a0years) being referred for speech concerns due to ankyloglossia were enrolled in a randomized trial and assigned to either a surgical intervention (N = 166) or a no surgical intervention (N = 175) group. Subsequently, patients were further categorized into 3 groups according to age: 2 to &lt; 3\u00a0years, 3 to &lt; 4\u00a0years, and 4 to &lt; 5\u00a0years. Measures of tongue appearance, tongue mobility, speech production, and parent and clinician intelligibility ratings were collected at preintervention (T0), 2-month postintervention (T1), 6-month postintervention (T2), and 12-month postintervention (T3).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>No statistically significant difference was found between surgical intervention and no surgical intervention groups for tongue appearance, tongue mobility, speech production, and intelligibility in the 2 to &lt; 3\u00a0years age. However, there was significantly improved speech production and intelligibility in the surgical intervention group when compared to the no surgical intervention group in the 3 to &lt; 4 and 4 to &lt; 5\u00a0years old age.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>Surgical intervention should not be performed too early for infants aged 2 to &lt; 3\u00a0years with speech articulation caused by ankyloglossia, but rather watch and wait for the physiological growth of the lingual frenulum. The optimal timing range for surgical intervention is 4 to 5\u00a0years. This should provide certain significant guidance for infants with speech articulation caused by ankyloglossia.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/01455613221087946","type":"journal-article","created":{"date-parts":[[2022,3,24]],"date-time":"2022-03-24T18:34:56Z","timestamp":1648146896000},"page":"787-793","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Efficacy of Infants Release of Ankyloglossia on Speech Articulation: A Randomized Trial"],"prefix":"10.1177","volume":"103","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9910-2984","authenticated-orcid":false,"given":"Hongfang","family":"Zhao","sequence":"first","affiliation":[{"name":"School of Stomatology, Lanzhou University, Lanzhou, Gansu, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoli","family":"He","sequence":"additional","affiliation":[{"name":"School of Stomatology, Lanzhou University, Lanzhou, Gansu, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianrong","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Petrochemical Engineering, Lanzhou University of Technology, Lanzhou, Gansu, People\u2019s Republic of China"},{"name":"Gansu Province Maternal and Child Health Hospital, Lanzhou, Gansu, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,3,24]]},"reference":[{"key":"bibr1-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1002\/ca.23343"},{"key":"bibr2-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2011-0077"},{"key":"bibr3-01455613221087946","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10024-3073"},{"issue":"1","key":"bibr4-01455613221087946","first-page":"79","volume":"23","author":"Brz\u0119cka D","year":"2019","journal-title":"Developmental period medicine"},{"key":"bibr5-01455613221087946","doi-asserted-by":"publisher","DOI":"10.5546\/aap.2021.eng.e600"},{"key":"bibr6-01455613221087946","doi-asserted-by":"publisher","DOI":"10.23804\/ejpd.2021.22.01.13"},{"key":"bibr7-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2019.01.019"},{"key":"bibr8-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1590\/S2179-64912012000400020"},{"key":"bibr9-01455613221087946","doi-asserted-by":"publisher","DOI":"10.3109\/14015439.2012.671357"},{"key":"bibr10-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2006.05.024"},{"issue":"1","key":"bibr11-01455613221087946","first-page":"69","volume":"21","author":"Yasuaki Mekaru KA","year":"2011","journal-title":"Oral Sci"},{"key":"bibr12-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2019.03.004"},{"key":"bibr13-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1177\/01455613211064045"},{"key":"bibr14-01455613221087946","volume-title":"Comparing Speech Assessments: The Usefulness of the DEAP as Compared to the GFTA-2","author":"Pitts AB","year":"2010"},{"key":"bibr15-01455613221087946","doi-asserted-by":"publisher","DOI":"10.4300\/jgme-d-15-00218.1"},{"key":"bibr16-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1111\/ipd.12802"},{"key":"bibr17-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2020.110035"},{"key":"bibr18-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-0660"},{"key":"bibr19-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1177\/0194599820925415"},{"key":"bibr20-01455613221087946","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph17030859"},{"key":"bibr21-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2013.11.006"},{"key":"bibr22-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1136\/bmjopen-2018-024800"},{"key":"bibr23-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1177\/2473974X19826943"},{"key":"bibr24-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1016\/j.revsto.2015.06.003"},{"key":"bibr25-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1111\/ped.12474"},{"key":"bibr26-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1016\/S0031-3955(03)00029-4"},{"key":"bibr27-01455613221087946","doi-asserted-by":"publisher","DOI":"10.4317\/medoral.20736"},{"key":"bibr28-01455613221087946","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-017-3871-4"}],"container-title":["Ear, Nose &amp; 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