{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:22:41Z","timestamp":1777562561426,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2022,5,29]],"date-time":"2022-05-29T00:00:00Z","timestamp":1653782400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:p>Laryngeal chondrosarcomas are rare tumors that account for only 0.2% of malignant tumors of the larynx. Approximately 80% of these tumors are low grade and well differentiated and are associated with a good long-term prognosis. Herein, we report a case of a 77-year-old male presenting with acute hypoxic respiratory failure that required intubation and mechanical ventilation. Chest CT showed multiple pulmonary nodules and cavities. He then required a tracheostomy, and a soft tissue mass in the subglottic mass was discovered. A laryngoscopy-guided excisional biopsy of the mass was performed. Histopathological examination confirmed the diagnosis of laryngeal chondrosarcoma. Clinicians should consider metastatic laryngeal chondrosarcoma as a differential diagnosis for lung cavities. Overall, we believe this to be the first case of aggressive laryngeal chondrosarcoma with mediastinal and pulmonary metastasis mimicking necrotizing pneumonia.<\/jats:p>","DOI":"10.1177\/01455613221100005","type":"journal-article","created":{"date-parts":[[2022,5,30]],"date-time":"2022-05-30T02:09:07Z","timestamp":1653876547000},"page":"NP116-NP120","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["A Rare Case of Aggressive Metastatic Laryngeal Chondrosarcoma Presenting as Bilateral Necrotizing Pneumonia"],"prefix":"10.1177","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1526-934X","authenticated-orcid":false,"given":"Noreen","family":"Mirza","sequence":"first","affiliation":[{"name":"Internal Medicine, Saint Michael\u2019s Medical Center, Newark, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sindhusha","family":"Veeraballi","sequence":"additional","affiliation":[{"name":"Internal Medicine, Saint Michael\u2019s Medical Center, Newark, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohammad Nabil","family":"Rayad","sequence":"additional","affiliation":[{"name":"Internal Medicine, Saint Michael\u2019s Medical Center, Newark, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fatima","family":"Kamal","sequence":"additional","affiliation":[{"name":"Medical Education, Saint Michael\u2019s Medical Center, Newark, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hamid","family":"Shaaban","sequence":"additional","affiliation":[{"name":"Hematology Oncology, Saint Michael\u2019s Medical Center, Newark, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Derek","family":"Lee","sequence":"additional","affiliation":[{"name":"Otolaryngology\/ENT, Saint Michael\u2019s Medical Center, Newark, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Savopoulos","sequence":"additional","affiliation":[{"name":"Hematology Oncology, Saint Michael\u2019s Medical Center, Newark, NJ, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,5,29]]},"reference":[{"key":"bibr1-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1002\/lary.26068"},{"key":"bibr2-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000337"},{"key":"bibr3-01455613221100005","first-page":"2925","volume":"27","author":"Sauter A","year":"2007","journal-title":"Anticancer Res"},{"key":"bibr4-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24416"},{"issue":"6","key":"bibr5-01455613221100005","first-page":"634","volume":"124","year":"2001","journal-title":"Thom\u00e9 R, Thom\u00e9 DC, de la Cortina RA Otolaryngol Head Neck Surg"},{"key":"bibr6-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1016\/j.anndiagpath.2017.05.010"},{"key":"bibr7-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjorl.2014.05.004"},{"key":"bibr8-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1017\/S002221510700076X"},{"key":"bibr9-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1002\/hed.20932"},{"key":"bibr10-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24518"},{"key":"bibr11-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejrad.2015.10.015"},{"issue":"4","key":"bibr12-01455613221100005","first-page":"553","volume":"19","author":"Lichtenstein L","year":"1943","journal-title":"American Journal of Pathology"},{"key":"bibr13-01455613221100005","doi-asserted-by":"publisher","DOI":"10.21037\/ajo-19-84"},{"key":"bibr14-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-013-2656-0"},{"key":"bibr15-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1002\/lary.22337"},{"key":"bibr16-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1002\/lary.24618"},{"key":"bibr17-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215100076714"},{"key":"bibr18-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1016\/j.anorl.2012.02.009"},{"key":"bibr19-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1002\/hed.21401"},{"key":"bibr20-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1002\/hed.23468"},{"key":"bibr21-01455613221100005","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2018.07.041"}],"container-title":["Ear, Nose &amp; 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