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The sinonasal tract is generally not affected by SFT, and less than 100 cases have been reported in the English literature to date. We report an extremely rare SFT of the nasal cavity and paranasal sinuses extending into the anterior frontal fossa through the floor of the anterior skull base. To our knowledge, this case is the fourth SFT of the sinonasal tract involving the anterior frontal fossa in the world. Meanwhile, the tumor, measuring 13 \u00d7 6 cm in images, is the largest SFT of the sinonasal tract compared to previously reported cases. Three surgical procedures, including a transcranial one, were performed for the patient to achieve complete removal of the tumor. The diagnosis of SFT was established primarily by immunohistochemical positivity for CD34, STAT6, and negativity for S-100 protein. We emphasize the possibility of recurrence in SFT, and close follow-up is necessary with the help of nasal endoscopy and imaging approaches.<\/jats:p>","DOI":"10.1177\/01455613221113809","type":"journal-article","created":{"date-parts":[[2022,7,17]],"date-time":"2022-07-17T21:34:00Z","timestamp":1658093640000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["A Large Solitary Fibrous Tumor of the Nasal Cavity and Paranasal Sinuses Involving the Anterior Frontal Fossa: A Case Report and Review of the Literature"],"prefix":"10.1177","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1225-6145","authenticated-orcid":false,"given":"Huachao","family":"Wu","sequence":"first","affiliation":[{"name":"Zhongnan Hospital of Wuhan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaoyan","family":"Hu","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenbin","family":"Xiang","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuomin","family":"Liu","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sha","family":"Fang","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ting","family":"Xu","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Qi","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Linhui","family":"Zheng","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wenqi","family":"Cai","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chaoyan","family":"Wu","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5346-7830","authenticated-orcid":false,"given":"Haijun","family":"Yu","sequence":"additional","affiliation":[{"name":"Zhongnan Hospital of Wuhan University"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2022,7,17]]},"reference":[{"key":"e_1_3_3_2_2","first-page":"385","article-title":"Primary neoplasms of the pleura: A report of five cases","volume":"11","author":"Klemperer P","year":"1931","unstructured":"Klemperer P, Rabin CB. 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