{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T07:02:23Z","timestamp":1783666943557,"version":"3.55.0"},"reference-count":22,"publisher":"SAGE Publications","issue":"7","license":[{"start":{"date-parts":[[2022,9,24]],"date-time":"2022-09-24T00:00:00Z","timestamp":1663977600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2022,9,24]],"date-time":"2022-09-24T00:00:00Z","timestamp":1663977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"This work was supported by the Science and Technology Program of Guangzhou, China","award":["201704030081"],"award-info":[{"award-number":["201704030081"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2025,7]]},"abstract":"<jats:sec>\n                    <jats:title>Objectives<\/jats:title>\n                    <jats:p>Our objective was to study the efficacy and safety of intratymapanic dexamethasone (ITD) for treating in M\u00e9niere\u2019s disease in southern China.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>A total of 124 patients with M\u00e9niere\u2019s disease were randomly divided into 2 groups: ITD group (n = 62) and intratympanic lidocaine (ITL) group (n = 62). The ITD group was further randomly divided into 2 groups based on dexamethasone dosage: ITD1 (2\u00a0mg\/ml) (n = 31) and ITD2 (5\u00a0mg\/ml) group (n = 31). Symptom alleviation and complications were recorded after every treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>\n                      Vertigo was improved in 65% of patients who received ITD compared with 55% of patients who received ITL patients (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      &lt; .05). Three patients in the ITD2 group had from otomycosis, and 2 of these patients had a perforation; no tympanic membrane perforation was observed in the ITL and ITD1 group.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Compared with lidocaine, dexamethasone is more effective in alleviating vertigo, and a lower concentration of dexamethasone can reduce the occurrence of complications.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/01455613221120729","type":"journal-article","created":{"date-parts":[[2022,9,24]],"date-time":"2022-09-24T05:10:50Z","timestamp":1663996250000},"page":"431-437","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Analysis of the Efficacy and Safety of Intratymapanic Dexamethasone for Treating Meniere\u2019s Disease: A Randomized Controlled Trial"],"prefix":"10.1177","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4988-1465","authenticated-orcid":false,"given":"Gendi","family":"Yin","sequence":"first","affiliation":[{"name":"The Third Affiliated Hospital of Sun Yat-Sen University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Zhicheng Li","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Sun Yat-Sen University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuqi","family":"Zhang","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Sun Yat-Sen University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyi","family":"Wang","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Sun Yat-Sen University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiali","family":"Yang","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Sun Yat-Sen University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hao","family":"Cai","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Sun Yat-Sen University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiangli","family":"Zeng","sequence":"additional","affiliation":[{"name":"The Third Affiliated Hospital of Sun Yat-Sen University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,9,24]]},"reference":[{"issue":"76","key":"e_1_3_3_2_2","first-page":"129","article-title":"Effect of intratympanic dexamethasone on controlling tinnitus and hearing loss in meniere\u2019s disease [corrected]","volume":"26","author":"Memari F","year":"2014","unstructured":"Memari F, Hassannia F. Effect of intratympanic dexamethasone on controlling tinnitus and hearing loss in meniere\u2019s disease [corrected]. Iran J Otorhinolaryngol. 2014;26(76):129-133. Erratum in: Iran J Otorhinolaryngol. 2014;26(77):270.","journal-title":"Iran J Otorhinolaryngol"},{"key":"e_1_3_3_3_2","first-page":"202","article-title":"Pregnancy rates from intrauterine insemination are equivalent following 1- versus 5-day letrozole administration for ovulation induction: A retrospective study","volume":"1","author":"McGrail K","year":"2020","unstructured":"McGrail K, Conway S, Storment J, Buzhardt S, Chappell N. Pregnancy rates from intrauterine insemination are equivalent following 1- versus 5-day letrozole administration for ovulation induction: A retrospective study. F S Rep. 2020;1:202-205.","journal-title":"F S Rep"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2018.1497805"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1985.00800100039001"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.3233\/VES-150549"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1996.01890140029007"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1990.01870040046011"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/myc.12979"},{"key":"e_1_3_3_10_2","first-page":"134","article-title":"Effect observation of cleaning up the external auditory canal by otoendoscope combined with clotrimazole ointment in the treatment of pregnancy with otitis externa mycotica","volume":"20","author":"Wei XM","year":"2018","unstructured":"Wei XM, Lu L, Gao X. Effect observation of cleaning up the external auditory canal by otoendoscope combined with clotrimazole ointment in the treatment of pregnancy with otitis externa mycotica. 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