{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T02:04:30Z","timestamp":1787018670194,"version":"build-2736575974"},"reference-count":16,"publisher":"SAGE Publications","issue":"10_suppl","license":[{"start":{"date-parts":[[2022,8,26]],"date-time":"2022-08-26T00:00:00Z","timestamp":1661472000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2022,12]]},"abstract":"<jats:p>Necrotizing tracheitis is a rare condition, mainly seen in immunocompromised patients, that may lead to pseudomembrane formation, airway obstruction and in severe cases, tracheal perforation. We present a case of a 32-year-old male with poorly controlled diabetes who presented with productive cough, dysphagia, and respiratory distress. Bronchoscopy revealed extensive tracheal necrosis along a 4-5\u00a0cm segment of cartilaginous trachea and was complicated by tracheal perforation with false passage into the anterior mediastinum. Once the airway was re-established, a multidisciplinary team discussed options for definitive airway management, including tracheal reconstruction, pulmonary stent, or tracheostomy. Ultimately, a distal XLT tracheostomy was placed. Microbiology specimens of the tracheal tissue were positive for Actinomyces. The patient was started on long-term antibiotics and diabetes management. At three-month follow-up, the trachea was patent with near complete mucosalization of the previously necrotic segment. An area of proximal tracheal stenosis was successfully managed with a customized tracheal T-tube. In conclusion, this is a case of necrotizing tracheitis complicated by tracheal perforation. Successful treatment required a multidisciplinary team for airway management as well as medical treatment of immunocompromising risk factors and antimicrobial therapy. This enabled timely healing of the trachea and a durable airway.<\/jats:p>","DOI":"10.1177\/01455613221123664","type":"journal-article","created":{"date-parts":[[2022,8,27]],"date-time":"2022-08-27T00:15:17Z","timestamp":1661559317000},"page":"26S-29S","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Necrotizing Tracheitis Complicated by Tracheal Wall Perforation"],"prefix":"10.1177","volume":"101","author":[{"given":"Bryan H.","family":"Louie","sequence":"first","affiliation":[{"name":"Department of Otolaryngology, University of California San Diego, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Stramiello","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University of California San Diego, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Grant","family":"Senyei","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Philip","family":"Weissbrod","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University of California San Diego, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joshua","family":"Boys","sequence":"additional","affiliation":[{"name":"Division of Cardiovascular and Thoracic Surgery, Department of Surgery, University of California San Diego, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George","family":"Cheng","sequence":"additional","affiliation":[{"name":"Division of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of California San Diego, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theresa","family":"Guo","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology, University of California San Diego, La Jolla, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,8,26]]},"reference":[{"key":"bibr1-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2013.03.017"},{"key":"bibr2-01455613221123664","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.02150"},{"key":"bibr3-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1086\/322674"},{"key":"bibr4-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e31826c2ccf"},{"key":"bibr5-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1177\/000348940711601001"},{"key":"bibr6-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4744-2"},{"key":"bibr7-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1080\/00365540510044445"},{"key":"bibr8-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1080\/00365540110077083"},{"key":"bibr9-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/13.1.73"},{"key":"bibr10-01455613221123664","doi-asserted-by":"publisher","DOI":"10.21037\/atm.2019.03.70"},{"key":"bibr11-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1097\/LBR.0000000000000300"},{"key":"bibr12-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm\/142.4.884"},{"key":"bibr13-01455613221123664","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2020.00360"},{"key":"bibr14-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.162.3.9910047"},{"key":"bibr15-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200112000-00015"},{"key":"bibr16-01455613221123664","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpge.2016.03.002"}],"container-title":["Ear, Nose &amp; 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