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They are commonly seen in joints and surrounding tissues, subcutaneous tissues, as well as the pinna and kidney, and are characteristic manifestations of gout. Vocal cord tophi are rarely reported in the literature, and patients often present with hoarseness, progressive dysphagia, and other symptoms. We report a case of a vocal cord mass found by gastroscopy in a patient with a history of gout for more than 20\u00a0years. Postoperative pathological findings were vocal cord tophi. Tophi can have serious consequences and should be included in the differential diagnosis of laryngeal masses in patients with a history of gout. Therapy should involve a combination of systemic uric acid-lowering treatment and surgery to improve symptoms and reduce recurrence.<\/jats:p>","DOI":"10.1177\/01455613221137225","type":"journal-article","created":{"date-parts":[[2022,11,24]],"date-time":"2022-11-24T09:45:48Z","timestamp":1669283148000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Vocal Cord Gout Nodules: A Case Report and Review of the Literature"],"prefix":"10.1177","volume":"104","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7670-1044","authenticated-orcid":false,"given":"Yan","family":"Wang","sequence":"first","affiliation":[{"name":"the First Affiliated Hospital of Kunming Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8258-4163","authenticated-orcid":false,"given":"Rongyue","family":"Ma","sequence":"additional","affiliation":[{"name":"the First Affiliated Hospital of Kunming Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biao","family":"Ruan","sequence":"additional","affiliation":[{"name":"the First Affiliated Hospital of Kunming Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Min","family":"Guo","sequence":"additional","affiliation":[{"name":"the First Affiliated Hospital of Kunming Medical University"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,11,24]]},"reference":[{"key":"e_1_3_5_2_2","doi-asserted-by":"publisher","DOI":"10.4081\/reumatismo.2011.238"},{"key":"e_1_3_5_3_2","doi-asserted-by":"publisher","DOI":"10.1038\/s41393-022-00773-2"},{"key":"e_1_3_5_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/BOR.0b013e3283361ac0"},{"key":"e_1_3_5_5_2","doi-asserted-by":"publisher","DOI":"10.1097\/SAP.0000000000001778"},{"key":"e_1_3_5_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000500514"},{"key":"e_1_3_5_7_2","doi-asserted-by":"publisher","DOI":"10.1258\/0022215021909890"},{"key":"e_1_3_5_8_2","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2010.0311"},{"key":"e_1_3_5_9_2","doi-asserted-by":"publisher","DOI":"10.1093\/jscr\/rjaa398"},{"key":"e_1_3_5_10_2","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/9786810"},{"key":"e_1_3_5_11_2","doi-asserted-by":"publisher","DOI":"10.3980\/j.issn.2222-3959.2013.03.09"},{"key":"e_1_3_5_12_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2014.12.015"},{"key":"e_1_3_5_13_2","doi-asserted-by":"publisher","DOI":"10.1024\/0040-5930\/a000769"},{"key":"e_1_3_5_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.arbres.2017.12.003"},{"key":"e_1_3_5_15_2","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-199902000-00019"},{"key":"e_1_3_5_16_2","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780080513"},{"key":"e_1_3_5_17_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2016.1819"},{"key":"e_1_3_5_18_2","doi-asserted-by":"publisher","DOI":"10.1055\/s-2001-16439"},{"key":"e_1_3_5_19_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348949110001108"},{"key":"e_1_3_5_20_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0385-8146(00)00119-X"},{"key":"e_1_3_5_21_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-008-1863-2"},{"key":"e_1_3_5_22_2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoto.2018.2253"},{"key":"e_1_3_5_23_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2019-231070"}],"container-title":["Ear, Nose &amp; Throat Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613221137225","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/01455613221137225","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613221137225","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:33:13Z","timestamp":1777401193000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/01455613221137225"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,11,24]]},"references-count":22,"journal-issue":{"issue":"1_suppl","published-print":{"date-parts":[[2025,3]]}},"alternative-id":["10.1177\/01455613221137225"],"URL":"https:\/\/doi.org\/10.1177\/01455613221137225","relation":{},"ISSN":["0145-5613","1942-7522"],"issn-type":[{"value":"0145-5613","type":"print"},{"value":"1942-7522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,11,24]]}}}