{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:04:31Z","timestamp":1777561471777,"version":"3.51.4"},"reference-count":30,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,6,8]],"date-time":"2023-06-08T00:00:00Z","timestamp":1686182400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Shanghai Municipal Key Clinical Specialty","award":["shslczdzk00801"],"award-info":[{"award-number":["shslczdzk00801"]}]},{"DOI":"10.13039\/501100014175","name":"Shanghai Municipal Health and Family Planning Commission","doi-asserted-by":"publisher","award":["2019SY059"],"award-info":[{"award-number":["2019SY059"]}],"id":[{"id":"10.13039\/501100014175","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["20Y11901900"],"award-info":[{"award-number":["20Y11901900"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003399","name":"Science and Technology Commission of Shanghai Municipality","doi-asserted-by":"publisher","award":["21Y11912000"],"award-info":[{"award-number":["21Y11912000"]}],"id":[{"id":"10.13039\/501100003399","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    <jats:bold>Objectives:<\/jats:bold>\n                    To evaluate the possible risk factors of obstructive sleep apnea (OSA) and its impact on the health-related quality of life (HRQoL) in patients with partial laryngectomy for laryngeal cancer.\n                    <jats:bold>Methods:<\/jats:bold>\n                    A cross-sectional method was used to carry out this study. Patients who underwent partial laryngectomy for laryngeal cancer completed overnight polygraphy (PG) home sleep tests and quality of life questionnaires. The Medical Outcome Study 36-item Short-Form Health Survey (SF-36) questionnaire was used to investigate the factors influencing HRQoL.\n                    <jats:bold>Results:<\/jats:bold>\n                    A total of 59 patients completed the PG tests and quality of life questionnaires, with 74.6% demonstrating evidence of OSA. There were significant differences in tumor area and neck dissection between OSA group and non-OSA groups. Based on sleep-related parameters, patients were divided into cluster 1 (n\u2009=\u200914) and cluster 2 (n\u2009=\u200945) using principal component analysis combined with K-means clustering. Two clusters had significantly different scores of body pain, general health, and health transition in SF-36 domains. Independent factors associated with general health were identified as tobacco use (OR\u2009=\u20094.716), alcohol use (OR\u2009=\u20093.193), and OSA-related condition (OR\u2009=\u200911.336).\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    Larger tumor area and neck dissection might be associated with an increased risk for developing OSA in patients with partial laryngectomy for laryngeal cancer. OSA partially mediated the effect on physical health, including body pain, general health, and health transition. It is important to be aware of the potential impact of OSA on diminished HRQoL of these patients.\n                  <\/jats:p>","DOI":"10.1177\/01455613231178955","type":"journal-article","created":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T01:22:37Z","timestamp":1686273757000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Impact of Obstructive Sleep Apnea on Health-Related Quality of Life in Patients With Partial Laryngectomy for Laryngeal Cancer"],"prefix":"10.1177","volume":"105","author":[{"given":"Min","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China"},{"name":"Shanghai Municipal Key Clinical Specialty, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Shi","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China"},{"name":"Shanghai Municipal Key Clinical Specialty, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7617-2832","authenticated-orcid":false,"given":"Haitao","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China"},{"name":"Shanghai Municipal Key Clinical Specialty, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6686-4846","authenticated-orcid":false,"given":"Lei","family":"Cheng","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China"},{"name":"Shanghai Municipal Key Clinical Specialty, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peijie","family":"He","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China"},{"name":"Shanghai Municipal Key Clinical Specialty, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qian","family":"Jin","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China"},{"name":"Shanghai Municipal Key Clinical Specialty, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9237-6595","authenticated-orcid":false,"given":"Jingjing","family":"Huang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Eye, Ear, Nose, and Throat Hospital, Fudan University, Shanghai, China"},{"name":"Shanghai Municipal Key Clinical Specialty, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,6,8]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.17219\/acem\/69693"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13849"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.3109\/0284186X.2014.925576"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1177\/0145561320929941"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdz074"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-020-07773-6"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.9134"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1186\/s40463-019-0347-6"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-020-06355-3"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.9772"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.3390\/medicina56080399"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinepi.2004.12.008"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.29857"},{"issue":"4","key":"e_1_3_2_16_2","first-page":"531","article-title":"The impact of obstructive sleep apnea syndrome severity on physical performance and mental health. the use of SF-36 questionnaire in sleep apnea","volume":"17","author":"Karkoulias K","year":"2013","unstructured":"Karkoulias K, Lykouras D, Sampsonas F, et al. 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