{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T12:00:11Z","timestamp":1791979211940,"version":"4.4.0"},"reference-count":12,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,6,17]],"date-time":"2023-06-17T00:00:00Z","timestamp":1686960000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,6,17]],"date-time":"2023-06-17T00:00:00Z","timestamp":1686960000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    <jats:bold>Introduction:<\/jats:bold>\n                    Sinonasal glomangiopericytoma (GPC) is an uncommon neoplasm, accounting for less than 0.5% of all sinonasal tumors. It is characterized as having low malignant potential, with complete surgical excision representing optimal treatment. Presenting symptoms are typically due to mass effect and vascularity of this tumor, often including unilateral nasal obstruction or epistaxis. Accounts of this tumor in the literature remain sparse.\n                    <jats:bold>Methods:<\/jats:bold>\n                    Single institution retrospective review.\n                    <jats:bold>Results:<\/jats:bold>\n                    Six cases of sinonasal GPC were identified from a review of the electronic medical records spanning from 2009 through 2021. Age at diagnosis ranged from 48 to 67\u2009years, with a gender distribution of 5 males and 1 female. Most subjects presented with unilateral sinonasal obstruction of variable duration. Each underwent endoscopic resection of the mass with negative margins, and no adjuvant therapy was pursued. Pathologic specimens demonstrated a vascular patterned tumor with spindled cells surrounding vessels and were positive for smooth muscle actin and negative for cytokeratin. Active post-surgical follow-up ranged from 11\u2009months to 10\u2009years. All patients were without endoscopic evidence of recurrence, and 2 had post-operative imaging which showed no evidence of disease.\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    This review of 6 cases of sinonasal GPC represents the largest known series of this rare pathology in the literature to date. Based on our experience, and in agreement with the available literature, this disease is reliably managed with complete surgical excision. Adjuvant therapy can be avoided in otherwise uncomplicated cases. Although rare, GPC should be considered in the differential diagnosis of all vascular sinonasal tumors.\n                  <\/jats:p>","DOI":"10.1177\/01455613231179688","type":"journal-article","created":{"date-parts":[[2023,6,17]],"date-time":"2023-06-17T07:31:45Z","timestamp":1686987105000},"page":"17-22","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":6,"title":["Single Institution Experience With Sinonasal Glomangiopericytoma: A Case Series"],"prefix":"10.1177","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7493-9844","authenticated-orcid":false,"given":"Natalie","family":"Schauwecker","sequence":"first","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seth","family":"Davis","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexander","family":"Perez","sequence":"additional","affiliation":[{"name":"Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alex","family":"Labby","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle","family":"Mannion","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9348-2165","authenticated-orcid":false,"given":"Robert","family":"Sinard","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"suffix":"Jr.","given":"James S.","family":"Lewis","sequence":"additional","affiliation":[{"name":"Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rick","family":"Chandra","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology-Head and Neck Surgery, Vanderbilt University Medical Center, Nashville, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,6,17]]},"reference":[{"issue":"4","key":"e_1_3_2_2_2","first-page":"593","article-title":"Sinonasal glomangiopericytoma: review of imaging appearance and clinical management update for a rare sinonasal neoplasm","volume":"94","author":"Al-Jobory YM","year":"2021","unstructured":"Al-Jobory YM, Pan Z, Manes RP, Omay SB, Ikuta I. Sinonasal glomangiopericytoma: review of imaging appearance and clinical management update for a rare sinonasal neoplasm. Yale J Biol Med. 2021;94(4):593-597.","journal-title":"Yale J Biol Med"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.33160\/yam.2019.06.009"},{"key":"e_1_3_2_4_2","first-page":"S1808","article-title":"Glomangiopericytoma: a case series with review of literature","volume":"88","author":"Kazi AA","year":"2021","unstructured":"Kazi AA, McDougal EM, Howell JB, Schuman TA, Nord RS. Glomangiopericytoma: a case series with review of literature. Braz J Otorhinolaryngol. 2021;88:S1808-8694.","journal-title":"Braz J Otorhinolaryngol"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1177\/014556131609500202"},{"key":"e_1_3_2_6_2","first-page":"43","volume-title":"World Health Organization Classification of Tumours: Pathology and Genetics of Head and Neck Tumours","author":"Thompson L","year":"2005","unstructured":"Thompson L, Fanburg-Smith JC, Wenig BM. Borderline and low malignant potential tumours of soft tissues. In: Barnes L, Eveson JW, Reichart P, Sidransky D, eds. World Health Organization Classification of Tumours: Pathology and Genetics of Head and Neck Tumours. 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