{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T17:36:48Z","timestamp":1780162608494,"version":"3.54.0"},"reference-count":52,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T00:00:00Z","timestamp":1686268800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,6,9]],"date-time":"2023-06-09T00:00:00Z","timestamp":1686268800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    <jats:bold>Objectives:<\/jats:bold>\n                    Laryngopharyngeal reflux (LPR) is a complex syndrome characterized by the reflux of gastroduodenal contents into the pharynx or larynx, resulting in a range of symptoms, including chronic cough, throat clearing, pain, dysphagia, hoarseness, and dysphonia. Despite the lack of a gold standard for diagnosis or treatment, various strategies have been proposed to manage LPR. However, the effectiveness of these treatments is compromised by the lack of a uniform treatment protocol, which places a burden on patients, physicians, and the healthcare system. This study aims to systematically review the treatments of LPR and provide updated and useful clinical information to clinical physicians.\n                    <jats:bold>Methods:<\/jats:bold>\n                    The literature with an emphasis on LPR and related keywords is searched and reviewed in PubMed.\n                    <jats:bold>Results:<\/jats:bold>\n                    Treatment of LPR includes health education, lifestyle modification, dietary changes, medications, and surgery, as well as the emergence of a novel treatment method involving external upper esophageal sphincter compression devices.\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    Currently, medication is the main treatment, supplemented with lifestyle and dietary changes, but there is still a lack of effective means for patients with drug-resistant or intolerant LPR. More high-quality and rigorous trials must continue to be conducted to determine the best treatment options and find novel treatments. Taking into account the complexity of LPR, this study proposes a simple algorithm to help clinicians with the initial management of this disease.\n                  <\/jats:p>","DOI":"10.1177\/01455613231180031","type":"journal-article","created":{"date-parts":[[2023,6,10]],"date-time":"2023-06-10T00:45:32Z","timestamp":1686357932000},"page":"55-61","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":7,"title":["Current Treatment of Laryngopharyngeal Reflux"],"prefix":"10.1177","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-5135-8129","authenticated-orcid":false,"given":"Yang","family":"Lin","sequence":"first","affiliation":[{"name":"School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shunlin","family":"Peng","sequence":"additional","affiliation":[{"name":"School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, People\u2019s Republic of China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,6,9]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1097\/MOO.0000000000000486"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27591"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)07665-1"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1590\/S0004-28032011000200003"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.alit.2019.04.011"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.5056\/jnm16057"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1111\/nyas.14728"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1111\/coa.13518"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-07201-w"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2020.110460"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00106-021-01006-3"},{"key":"e_1_3_2_13_2","first-page":"61","article-title":"Magnesium alginate in patients with laryngopharyngeal reflux","volume":"35","author":"Ciprandi G","year":"2021","unstructured":"Ciprandi G, Damiani V, Passali FM, Crisanti A, Motta G, Passali D. 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