{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,10]],"date-time":"2026-07-10T17:56:54Z","timestamp":1783706214205,"version":"3.55.0"},"reference-count":21,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T00:00:00Z","timestamp":1694476800000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,9,12]],"date-time":"2023-09-12T00:00:00Z","timestamp":1694476800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2026,4]]},"abstract":"<jats:p>Thyroglossal duct cyst carcinoma (TGDCCa) is a rare condition with only approximately 300 cases reported to date. There is a lack of comprehensive reporting on its clinical manifestations, ultrasound, contrast-enhanced computed tomography, magnetic resonance imaging (MRI) features, immunophenotyping, procedure, and prognosis following modified Sistrunk\u2019s procedure. This study aimed to address these gaps by analyzing and summarizing the clinical features of 5 cases of papillary carcinoma arising in thyroglossal duct cysts (TGDC).<\/jats:p>\n                  <jats:p>\n                    Five patients with papillary carcinoma in TGDC treated by modified Sistrunk\u2019s procedure were included. Their clinical manifestation, physical examination findings, iconography, pathological findings, treatment, and outcomes were analyzed in aiding the diagnosis and treatment of TGDCCa. Immunohistochemistry was used to confirm the papillary carcinoma subtype. The\n                    <jats:italic toggle=\"yes\">BRAF<\/jats:italic>\n                    <jats:sup>V600E<\/jats:sup>\n                    mutation was detected in 2 patients. No evidence of cancer recurrence, distant metastases, and malignant changes in the thyroid was found after a mean follow-up of 29.8 months.\n                  <\/jats:p>\n                  <jats:p>The management of TGDCCa with papillary carcinoma in low-risk patients can be accomplished by performing a modified Sistrunk\u2019s procedure along with a regular follow-up imaging of the thyroid and neck. Although postoperative pathological diagnosis is the gold standard for diagnosis, it is equally crucial to comprehend the clinical manifestations and auxiliary diagnostic techniques before surgical intervention.<\/jats:p>","DOI":"10.1177\/01455613231181710","type":"journal-article","created":{"date-parts":[[2023,9,13]],"date-time":"2023-09-13T02:35:53Z","timestamp":1694572553000},"page":"252-260","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Clinical Observation and Analysis of Thyroglossal Duct Cyst Carcinoma: A Report of 5 Cases"],"prefix":"10.1177","volume":"105","author":[{"given":"Lei","family":"Lei","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology, Head &amp; Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-8734-5306","authenticated-orcid":false,"given":"Min","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head &amp; Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zongguo","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of Pathology, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Zou","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head &amp; Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lin","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, West China Medical School, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"NingYing","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head &amp; Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jifeng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Head &amp; Neck Surgery, West China Hospital, West China Medical School, Sichuan University, Chengdu, Sichuan, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2023,9,12]]},"reference":[{"key":"e_1_3_2_2_2","first-page":"665","article-title":"Struma aberrata lingual mit druzenmetastasen","volume":"37","author":"Brentano H","year":"1911","unstructured":"Brentano H. Struma aberrata lingual mit druzenmetastasen. Dtsch Med Wochenschr. 1911;37:665-666.","journal-title":"Dtsch Med Wochenschr"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/0194599817696504"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.4065\/72.4.315"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.5603\/EP.a2020.0010"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2017.02.007"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2016.07.024"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1007\/s13304-019-00684-7"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2013.10.003"},{"key":"e_1_3_2_10_2","first-page":"1","article-title":"Standard for diagnosis and treatment of thyroid cancer (2018 Edition)","volume":"13","author":"State Health Commission of the People\u2019s Republic of China","year":"2019","unstructured":"State Health Commission of the People\u2019s Republic of China. 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