{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:05:06Z","timestamp":1777561506955,"version":"3.51.4"},"reference-count":22,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T00:00:00Z","timestamp":1687305600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T00:00:00Z","timestamp":1687305600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Shanghai Medical Innovation Project","award":["22Y11902100"],"award-info":[{"award-number":["22Y11902100"]}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of Chain","doi-asserted-by":"crossref","award":["82071040"],"award-info":[{"award-number":["82071040"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2026,1]]},"abstract":"<jats:p>\n                    <jats:bold>Objective:<\/jats:bold>\n                    To compare the graft success rate and hearing outcomes of endoscopic cartilage reinforcement perichondrium-cartilage composite graft and push-through techniques for the treatment of large marginal perforations.\n                    <jats:bold>Study Design:<\/jats:bold>\n                    Randomized controlled trial.\n                    <jats:bold>Materials and Methods:<\/jats:bold>\n                    A total of 57 large marginal perforations were prospectively randomized to cartilage reinforcement (n\u2009=\u200929) and cartilage push-through technique (n\u2009=\u200928) groups. The graft success rate, audiometric outcomes, and complications were compared between the 2 groups at 6\u2009months.\n                    <jats:bold>Results:<\/jats:bold>\n                    All patients completed 6\u2009months of follow-up. The graft success rate in the cartilage reinforcement group was significantly higher compared to that in the push-through group (100.0% vs 78.6%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.01). Residual perforation was observed in 5 (17.9%) patients, and re-perforation in 1 (3.6%) patient, in the push-through group. The preoperative air-bone gap (ABG) was 17.6\u2009\u00b1\u20093.5\u2009dB in the cartilage reinforcement group and 16.8\u2009\u00b1\u20098.4\u2009dB in the push-through group (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&gt;\u2009.05). Postoperatively, although the postoperative ABG in the cartilage reinforcement group was higher than that in the push-through group, no significant difference was observed (11.8\u2009\u00b1\u20094.3\u2009dB vs 8.9\u2009\u00b1\u20092.5\u2009dB,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&gt;\u2009.05). Additionally, no significant difference was found in ABG closure between the 2 groups (6.6\u2009\u00b1\u20091.9\u2009dB vs 7.9\u2009\u00b1\u20094.7\u2009dB,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&gt;\u2009.05).\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    Cartilage reinforcement myringoplasty is a simpler and more useful technique to achieve graft success compared to cartilage-perichondrium push-through for the treatment of large marginal perforations, and it does not affect hearing levels.\n                  <\/jats:p>","DOI":"10.1177\/01455613231182661","type":"journal-article","created":{"date-parts":[[2023,6,21]],"date-time":"2023-06-21T06:09:42Z","timestamp":1687327782000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":5,"title":["Comparison of Cartilage Reinforcement and Push-Through Techniques for the Treatment of Large Perforations"],"prefix":"10.1177","volume":"105","author":[{"given":"Zihan","family":"Lou","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Department of Otolaryngology Head and Neck Surgery &amp; Center of Sleep Medicine, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Otolaryngological Institute of Shanghai Jiao Tong University, Shanghai, China"},{"name":"Shanghai Key Lab Sleep Disordered Breathing, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1085-9033","authenticated-orcid":false,"given":"Zhengcai","family":"Lou","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Wenzhou Medical University Affiliated Yiwu Hospital, Yiwu, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingjing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Department of Otolaryngology Head and Neck Surgery &amp; Center of Sleep Medicine, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Otolaryngological Institute of Shanghai Jiao Tong University, Shanghai, China"},{"name":"Shanghai Key Lab Sleep Disordered Breathing, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boya","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Department of Otolaryngology Head and Neck Surgery &amp; Center of Sleep Medicine, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Otolaryngological Institute of Shanghai Jiao Tong University, Shanghai, China"},{"name":"Shanghai Key Lab Sleep Disordered Breathing, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yibing","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Department of Otolaryngology Head and Neck Surgery &amp; Center of Sleep Medicine, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Otolaryngological Institute of Shanghai Jiao Tong University, Shanghai, China"},{"name":"Shanghai Key Lab Sleep Disordered Breathing, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7774-441X","authenticated-orcid":false,"given":"Zhengnong","family":"Chen","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Department of Otolaryngology Head and Neck Surgery &amp; Center of Sleep Medicine, Shanghai Sixth People\u2019s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China"},{"name":"Otolaryngological Institute of Shanghai Jiao Tong University, Shanghai, China"},{"name":"Shanghai Key Lab Sleep Disordered Breathing, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,6,21]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/0145561320946908"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1002\/lary.27325"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.976"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1080\/00016489.2021.1962545"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215120000006"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3342\/ceo.2015.8.3.224"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1017\/S0022215118000762"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-011-1779-4"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003141"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-021-06913-3"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000006459"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003138"},{"key":"e_1_3_2_14_2","volume-title":"Otolaryngol Head Neck Surg","author":"Eren SB","unstructured":"Eren SB, Tugrul S, Ozucer B, Veyseller B, Aksoy F, Ozturan O. 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