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A revision tympanoplasty with mastoidectomy was performed, and during the postoperative period, the patient had persistent pain and otorrhea, which were managed with opioids and several courses of antibiotic therapy. After symptoms persisted, imaging and culture ultimately led to the diagnosis of fungal skull base osteomyelitis, which was eventually treated successfully. While these complications are rare, their likelihood is increased with treatment delay and in the immunocompromised patient. Close management of immunocompromised patients, including diabetic patients, is vital in identifying complications early to aid in timely diagnosis and treatment to lead to the best possible outcome.<\/jats:p>","DOI":"10.1177\/01455613231189219","type":"journal-article","created":{"date-parts":[[2023,7,29]],"date-time":"2023-07-29T02:05:11Z","timestamp":1690596311000},"page":"31S-34S","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Complex Case of Skull Base Osteomyelitis Secondary to Chronic Otitis Media"],"prefix":"10.1177","volume":"102","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1709-8449","authenticated-orcid":false,"given":"Masa","family":"Petrovic","sequence":"first","affiliation":[{"name":"Faculty of Medicine, University of Belgrade, Belgrade, Serbia"},{"name":"Institute for Cardiovascular Diseases \u201cDedinje\u201d, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3887-9236","authenticated-orcid":false,"given":"Hannah G.","family":"Landsberger","sequence":"additional","affiliation":[{"name":"Department of Surgery, Long Island Jewish Medical Center, Northwell Health, New Hyde Park, NY, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin A.","family":"Peng","sequence":"additional","affiliation":[{"name":"House Institute, Los Angeles, CA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,7,28]]},"reference":[{"key":"bibr1-01455613231189219","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.24144"},{"key":"bibr2-01455613231189219","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.13394"},{"key":"bibr3-01455613231189219","doi-asserted-by":"publisher","DOI":"10.5152\/iao.2020.7709"},{"issue":"6","key":"bibr4-01455613231189219","first-page":"416","volume":"32","author":"Bovo R","year":"2012","journal-title":"Acta Otorhinolaryngol Ital"},{"key":"bibr5-01455613231189219","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000007508"},{"key":"bibr6-01455613231189219","doi-asserted-by":"publisher","DOI":"10.1093\/ageing\/afz003"},{"key":"bibr7-01455613231189219","doi-asserted-by":"publisher","DOI":"10.4103\/ajns.AJNS_90_17"},{"key":"bibr8-01455613231189219","doi-asserted-by":"publisher","DOI":"10.1186\/s12880-019-0331-7"}],"container-title":["Ear, Nose &amp; Throat Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613231189219","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/01455613231189219","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613231189219","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:34:00Z","timestamp":1777401240000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/01455613231189219"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7,28]]},"references-count":8,"journal-issue":{"issue":"9_suppl","published-print":{"date-parts":[[2023,9]]}},"alternative-id":["10.1177\/01455613231189219"],"URL":"https:\/\/doi.org\/10.1177\/01455613231189219","relation":{},"ISSN":["0145-5613","1942-7522"],"issn-type":[{"value":"0145-5613","type":"print"},{"value":"1942-7522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,7,28]]}}}