{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,12]],"date-time":"2026-08-12T06:27:50Z","timestamp":1786516070237,"version":"build-2736575974"},"reference-count":21,"publisher":"SAGE Publications","issue":"8","license":[{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2024,2,6]],"date-time":"2024-02-06T00:00:00Z","timestamp":1707177600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2026,8]]},"abstract":"<jats:p>\n                    <jats:bold>Objectives:<\/jats:bold>\n                    The primary objective was to identify the incidence of neoplastic disease in patients referred for epistaxis. Secondary objectives included identification of any mass lesion, and the need for further workup with imaging and\/or biopsy as well as risk factors associated with identification of a mass lesion.\n                    <jats:bold>Study Design:<\/jats:bold>\n                    Retrospective cohort study.\n                    <jats:bold>Methods:<\/jats:bold>\n                    Medical records of adult patients who presented to Tufts Medical Center over an 11\u2009year period (2010-2021) with a chief complaint of epistaxis were reviewed. The primary outcome was identification of a nasal or nasopharyngeal mass. Patient characteristics including age, sex, race, smoking status, anticoagulation, comorbidities (hypertension, allergic rhinitis, vasculitis), and treatment of epistaxis (used as surrogate for severity of epistaxis) were also examined.\n                    <jats:bold>Results:<\/jats:bold>\n                    A total of 1164 patients met inclusion and exclusion criteria. Thirty-six nasal masses were found among patients presenting with epistaxis (3.09%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009&lt;\u2009.001), comprised primarily of benign etiology (2.66%) including nasal polyposis and thornwaldt cyst. Asian race correlated with finding of mass lesion (75%,\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    \u2009=\u2009.007). Five malignancies were found (0.43%) including nasopharyngeal carcinoma (2 patients), extranodal natural killer T-cell lymphoma (2 patients), and nasal adenocarcinoma (1 patient).\n                    <jats:bold>Conclusions:<\/jats:bold>\n                    Epistaxis is a common cause for referral to otolaryngology. Although the incidence of neoplasm in our patient population was low, nasal mass lesions warranting further workup were identified in 36 patients. Findings of neoplasm were more common in patients of Asian ethnicity, which may reflect the increased prevalence of nasopharyngeal carcinoma in this population. Otolaryngologic evaluation and nasal endoscopy should be considered in all cases of epistaxis.\n                  <\/jats:p>","DOI":"10.1177\/01455613231223946","type":"journal-article","created":{"date-parts":[[2024,2,7]],"date-time":"2024-02-07T00:47:12Z","timestamp":1707266832000},"page":"504-509","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Incidence of Neoplasm in Patients Referred for Epistaxis"],"prefix":"10.1177","volume":"105","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0637-7103","authenticated-orcid":false,"given":"Nicholas","family":"Toomey","sequence":"first","affiliation":[{"name":"UC Davis Health Department of Otolaryngology, Sacramento, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tania","family":"Hassanzadeh","sequence":"additional","affiliation":[{"name":"Tufts Medical Center Department of Otolaryngology, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"O\u2019Neil Danis","sequence":"additional","affiliation":[{"name":"Tufts Medical Center Department of Otolaryngology, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeremiah","family":"Tracy","sequence":"additional","affiliation":[{"name":"Tufts Medical Center Department of Otolaryngology, Boston, MA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,6]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1177\/0194599819890327"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2006.01.005"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0b013e318064c711"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.2500\/ajr.2006.20.2878"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21660"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-06-0353"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)00055-0"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.1016\/0360-3016(95)00516-2"},{"key":"e_1_3_2_10_2","volume-title":"The Python Language Reference Manual","author":"Van Rossum G","year":"2011","unstructured":"Van Rossum G, Drake FL. 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