{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T05:05:37Z","timestamp":1781413537744,"version":"3.54.1"},"reference-count":9,"publisher":"SAGE Publications","issue":"4","license":[{"start":{"date-parts":[[2024,1,20]],"date-time":"2024-01-20T00:00:00Z","timestamp":1705708800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,1,20]],"date-time":"2024-01-20T00:00:00Z","timestamp":1705708800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100030943","name":"Chosun University Hospital","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100030943","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2025,4]]},"abstract":"<jats:p>Anaplastic thyroid cancer (ATC), a rare thyroid malignancy, accounts for only 5% of all thyroid cancers. However, it is the most aggressive form and has a very poor prognosis. Increasing evidence suggests that ATC arises from papillary thyroid carcinoma (PTC). However, the exact mechanism underlying this transformation remains unclear. In almost all cases, ATC originates within, but rarely outside, the thyroid gland. Transformation of metastatic PTC into ATC within the cervical lymph nodes is extremely rare. In this report, we present a rare case in a 63-year-old male patient who was initially diagnosed with PTC at his first hospital visit, which underwent anaplastic transformation in lymph node metastasis, and was subsequently diagnosed during the follow-up visit.<\/jats:p>","DOI":"10.1177\/01455613231225872","type":"journal-article","created":{"date-parts":[[2024,1,20]],"date-time":"2024-01-20T06:29:34Z","timestamp":1705732174000},"page":"228-231","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Anaplastic Transformation in Papillary Thyroid Carcinoma: A Case Report"],"prefix":"10.1177","volume":"104","author":[{"given":"Young Sang","family":"Lyu","sequence":"first","affiliation":[{"name":"Division of Endocrinology and Metabolism, Department of Internal Medicine, Chosun University Hospital, Gwangju, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ran","family":"Hong","sequence":"additional","affiliation":[{"name":"Department of Pathology, Chosun University College of Medicine, Gwangju, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3774-1406","authenticated-orcid":false,"given":"Jeonghyun","family":"Oh","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology-Head and Neck Surgery, Chosun University College of Medicine, Gwangju, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,1,20]]},"reference":[{"issue":"9","key":"e_1_3_2_2_2","first-page":"5888","article-title":"The incidence and survival analysis for anaplastic thyroid cancer: a SEER database analysis","volume":"11","author":"Lin B","year":"2019","unstructured":"Lin B, Ma H, Ma M, Zhang Z, Sun Z, Hsieh I-Y, et al. The incidence and survival analysis for anaplastic thyroid cancer: a SEER database analysis. Am J Transl Res. 2019;11(9):5888.","journal-title":"Am J Transl Res"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1677\/ERC-08-0154"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2006.05.042"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1089\/thy.2012.0302"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12022-022-09707-3"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14041061"},{"key":"e_1_3_2_8_2","article-title":"De-differentiation of papillary thyroid carcinoma into squamous cell carcinoma. A case of coexistence within an excised neck lesion","volume":"2012","author":"Evans WDG","year":"2012","unstructured":"Evans WDG. De-differentiation of papillary thyroid carcinoma into squamous cell carcinoma. A case of coexistence within an excised neck lesion. 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