{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T05:19:09Z","timestamp":1787807949211,"version":"build-2784847793"},"reference-count":38,"publisher":"SAGE Publications","issue":"9","license":[{"start":{"date-parts":[[2024,2,12]],"date-time":"2024-02-12T00:00:00Z","timestamp":1707696000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2024,2,12]],"date-time":"2024-02-12T00:00:00Z","timestamp":1707696000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Clinical research on health industry of Shanghai Health Commission","award":["20214Y0025"],"award-info":[{"award-number":["20214Y0025"]}]},{"name":"research of Shanghai Pudong District Health Commission","award":["PW2022A-41"],"award-info":[{"award-number":["PW2022A-41"]}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"published-print":{"date-parts":[[2026,9]]},"abstract":"<jats:p>\n                    <jats:bold>Objectives:<\/jats:bold>\n                    Understanding the interaction between marital status and gender, race, and age is important for developing tailored interventions aimed at improving socio-emotional support for patients. Therefore, the objective of this study is to explore the correlation between marital status and hypopharynx squamous cell carcinoma (SCC) and whether the association varied by age, race, and gender.\n                    <jats:bold>Methods:<\/jats:bold>\n                    We examined the clinicopathological variables using chi-squared tests and we evaluated the association between survival and different variables using the methods of Kaplan-Meier. Univariate and multivariate analyses were performed to determine the effects of each variable on survival.\n                    <jats:bold>Results:<\/jats:bold>\n                    A total of 1686 patients were analyzed. The rate of being married was lower among African American, and this rate decreased with higher tumor stage. While both married male and female survivors benefit from their marital status, subgroups analysis shows a differential in overall survival (OS) based on gender, with males benefiting more than females. Patients who were divorced\/separated [male hazard ratio (HR) = 1.214, 95% confidence interval (CI): 0.985-1.495; female HR = 1. 159, 95% CI: 0.691-1.945], never married (male HR = 1.476, 95% CI: 1.234-1.765; female HR = 1.422, 95% CI: 0.901-2.245), and widowed (male HR = 1.795, 95% CI: 1.390-2.317; female HR = 1.663, 95% CI: 1.081-2.559) had increased hazard of OS compared with married\/partnered patients. The effect of marital status was significantly associated with treatment outcome only in Caucasian patients who harbored well\/moderately differentiated and nonmetastatic disease (\n                    <jats:italic toggle=\"yes\">P<\/jats:italic>\n                    &lt; .001).\n                    <jats:bold>Conclusion:<\/jats:bold>\n                    While there are survival benefits for married patients with hypopharynx SCC, married\/partnered males may benefit more than females. Age, race, and gender could affect the correlation between marital status and survival.\n                  <\/jats:p>","DOI":"10.1177\/01455613241228079","type":"journal-article","created":{"date-parts":[[2024,2,12]],"date-time":"2024-02-12T06:26:35Z","timestamp":1707719195000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Effects of Marital Status on Hypopharynx Squamous Cell Carcinoma Survival Stratified by Demographic and Pathological Factors: A Retrospective Study"],"prefix":"10.1177","volume":"105","author":[{"given":"Yujiao","family":"Li","sequence":"first","affiliation":[{"name":"Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Shanghai, China"},{"name":"Shanghai Key Laboratory of Radiation Oncology (20dz2261000), Shanghai, China"},{"name":"Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, China"},{"name":"Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China"},{"name":"Department of Oncology, Shanghai Medical College, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dan","family":"You","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Shanghai, China"},{"name":"Shanghai Key Laboratory of Radiation Oncology (20dz2261000), Shanghai, China"},{"name":"Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, China"},{"name":"Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China"},{"name":"Department of Oncology, Shanghai Medical College, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0811-8180","authenticated-orcid":false,"given":"Chaosu","family":"Hu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, Shanghai, China"},{"name":"Shanghai Key Laboratory of Radiation Oncology (20dz2261000), Shanghai, China"},{"name":"Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy, Shanghai, China"},{"name":"Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China"},{"name":"Department of Oncology, Shanghai Medical College, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,2,12]]},"reference":[{"issue":"1","key":"e_1_3_2_2_2","first-page":"43","article-title":"Association between head and neck squamous cell carcinoma survival, smoking at diagnosis, and marital status","volume":"144","author":"Osazuwa-Peters N","year":"2018","unstructured":"Osazuwa-Peters N, Boakye EA, Chen BY, Tobo BB, Varvares MA. Association between head and neck squamous cell carcinoma survival, smoking at diagnosis, and marital status. 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