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Up to now, fewer than 70 cases have been reported. Several postulates, including the fusion theory, merging theory, and invagination theory, have been proposed to explain the formation of the congenital midline sinus of the upper lip. Nevertheless, the etiology of this uncommon abnormality remains unclear. This report details a case of a congenital upper lip sinus presenting as a congenital midline sinus of the upper lip and reviews the current literature on this condition.<\/jats:p>","DOI":"10.1177\/01455613241249052","type":"journal-article","created":{"date-parts":[[2024,4,22]],"date-time":"2024-04-22T04:27:50Z","timestamp":1713760070000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Congenital Midline Upper Lip Sinus: Case Report and Review of the Literature"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0008-3963-6504","authenticated-orcid":false,"given":"Peng","family":"Li","sequence":"first","affiliation":[{"name":"School of Clinical Medicine, Shandong Second Medical University, Weifang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jingyuan","family":"Wang","sequence":"additional","affiliation":[{"name":"School of Clinical Medicine, Shandong Second Medical University, Weifang, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-0253-6300","authenticated-orcid":false,"given":"Liqiang","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Linyi People\u2019s Hospital, Linyi, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,4,22]]},"reference":[{"key":"bibr1-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_2002_039_0457_ulftnc_2.0.co_2"},{"key":"bibr2-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijporl.2022.111394"},{"key":"bibr3-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2018.08.012"},{"key":"bibr4-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-197312000-00017"},{"key":"bibr5-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-018-1399-z"},{"key":"bibr6-01455613241249052","volume":"2016","author":"Hili S","year":"2016","journal-title":"BMJ Case Rep"},{"key":"bibr7-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1017\/S002221510007184X"},{"key":"bibr8-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-0503(73)80026-8"},{"key":"bibr9-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1973.00780010267008"},{"issue":"2","key":"bibr10-01455613241249052","first-page":"215","volume":"19","author":"Grenman R","year":"1985","journal-title":"Scand J Plast Reconstr Surg"},{"key":"bibr11-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1097\/00006534-198005000-00022"},{"key":"bibr12-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-199209000-00013"},{"key":"bibr13-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1097\/00000637-200044010-00013"},{"key":"bibr14-01455613241249052","doi-asserted-by":"publisher","DOI":"10.11622\/smedj.2015096"},{"key":"bibr15-01455613241249052","doi-asserted-by":"publisher","DOI":"10.3174\/ajnr.A3453"},{"key":"bibr16-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1597\/12-046r"},{"key":"bibr17-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2020.03.004"},{"key":"bibr18-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1016\/S0901-5027(89)80061-X"},{"key":"bibr19-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1016\/S0901-5027(05)80445-X"},{"key":"bibr20-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1597\/1545-1569_1997_034_0083_cmsotu_2.3.co_2"},{"key":"bibr21-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1016\/S0901-5027(99)80672-9"},{"key":"bibr22-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0000000000002568"},{"key":"bibr23-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-016-1044-7"},{"key":"bibr24-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1177\/1055665617723635"},{"key":"bibr25-01455613241249052","doi-asserted-by":"publisher","DOI":"10.1111\/cga.12459"}],"container-title":["Ear, Nose &amp; 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