{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:18:09Z","timestamp":1777562289792,"version":"3.51.4"},"reference-count":21,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T00:00:00Z","timestamp":1732060800000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["Grant Nos. 82271166"],"award-info":[{"award-number":["Grant Nos. 82271166"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100007219","name":"Natural Science Foundation of Shanghai Municipality","doi-asserted-by":"publisher","award":["Grant No.22ZR1410100 to DR"],"award-info":[{"award-number":["Grant No.22ZR1410100 to DR"]}],"id":[{"id":"10.13039\/100007219","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["81970880 to DR"],"award-info":[{"award-number":["81970880 to DR"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"abstract":"<jats:p>Objective: To analyze the clinical effect of tympanoplasty performed for chronic suppurative otitis media (CSOM) patients with otomycosis under the oto-endoscope. Methods: A retrospective analysis was conducted on the healing of the tympanic membrane and hearing improvement of 431 CSOM patients who underwent endoscopic type 1 tympanoplasty. The patients with CSOM were divided into the control group ( n = 203, without otomycosis) and the trial group ( n = 184, with otomycosis). The patients were followed up for at least 3 months. The graft uptake rate and hearing improvement were compared. Results: The graft uptake rate was 94.57% (174\/184) in the trial group and 96.06% (195\/203) in the control group, indicating no significant difference between the 2 groups. The preoperative and postoperative average air-conduction hearing thresholds of CSOM with otomycosis were 42.68 \u00b1 11.46 dBHL and 33.01 \u00b1 11.51 dBHL, respectively ( P = .000). Mean air-bone gap (ABG) reduction values were 3.96 \u00b1 7.20 dBHL and 3.34 \u00b1 7.96 dBHL, respectively. There was no significant difference in the average ABG ( P = .420) and average air-conduction hearing threshold ( P = .649) between the trial group and the control group after operation. The culture results of the CSOM group with otomycosis showed that the most common fungal genus was Aspergillus (87\/173), with 32 cases of mixed infection of fungi and bacteria, and the most common mixed infection of bacteria was Staphylococcus epidermidis (9\/32). The failure graft uptake was noticed in 8.8% (5\/57) cases in the trial group with postoperative fungal infection and 3.9% (5\/127) without otomycosis ( P = .289). No significant difference was found in the successful healing rate among age, duration, perforation size, fungal type, postoperative fungal infection. Conclusion: CSOM with otomycosis is not a contraindication for endoscopic type 1 tympanoplasty, and external auditory canal fungal infection does not affect postoperative healing and hearing improvement. Intraoperative repeated rinsing with povidone-iodine may reduce the occurrence of postoperative infection.<\/jats:p>","DOI":"10.1177\/01455613241300891","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T23:37:02Z","timestamp":1732145822000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":3,"title":["Efficacy Analysis of Endoscopic Type 1 Tympanoplasty for Chronic Suppurative Otitis Media with Otomycosis"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0005-2179-5484","authenticated-orcid":false,"given":"Linglan","family":"Gu","sequence":"first","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China"},{"name":"NHC Key Laboratory of Hearing Medicine Research, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuhui","family":"Deng","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Minhang Branch, Zhongshan Hospital, Fudan University, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ying","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, Southern Central Hospital of Yunnan Province, Yunnan, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7395-9525","authenticated-orcid":false,"given":"Wuqing","family":"Wang","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China"},{"name":"NHC Key Laboratory of Hearing Medicine Research, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2889-9375","authenticated-orcid":false,"given":"Dongdong","family":"Ren","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China"},{"name":"NHC Key Laboratory of Hearing Medicine Research, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jianghong","family":"Xu","sequence":"additional","affiliation":[{"name":"ENT Institute and Department of Otorhinolaryngology, Eye & ENT Hospital, Fudan University, Shanghai, China"},{"name":"NHC Key Laboratory of Hearing Medicine Research, Shanghai, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2024,11,20]]},"reference":[{"key":"bibr1-01455613241300891","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.2009.tb02925.x"},{"key":"bibr2-01455613241300891","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1177\/014556130208100102","volume":"81","author":"Roland PS","year":"2002","journal-title":"Ear Nose Throat J"},{"key":"bibr3-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2020.09.010"},{"key":"bibr4-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1016\/j.joto.2019.11.004"},{"key":"bibr5-01455613241300891","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10071541"},{"key":"bibr6-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1016\/j.otohns.2006.07.008"},{"key":"bibr7-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1590\/S1808-86942009000300010"},{"key":"bibr8-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1097\/00005537-200004000-00003"},{"key":"bibr9-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1177\/0145561321999263"},{"key":"bibr10-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1016\/j.anl.2023.09.003"},{"key":"bibr11-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1002\/lary.30479"},{"key":"bibr12-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-019-05636-w"},{"key":"bibr13-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1097\/MAO.0000000000003940"},{"key":"bibr14-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1016\/j.asjsur.2023.02.114"},{"key":"bibr15-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2020.102744"},{"key":"bibr16-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1016\/j.berh.2019.101477"},{"key":"bibr17-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1177\/0145561319851499"},{"key":"bibr18-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1001\/archoto.2011.10"},{"key":"bibr19-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjoto.2020.102493"},{"key":"bibr20-01455613241300891","doi-asserted-by":"publisher","DOI":"10.1177\/014556131409300811"},{"key":"bibr21-01455613241300891","doi-asserted-by":"publisher","DOI":"10.14639\/0392-100X-N1369"}],"container-title":["Ear, Nose &amp; 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