{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,4]],"date-time":"2026-08-04T08:36:50Z","timestamp":1785832610616,"version":"3.56.0"},"reference-count":12,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T00:00:00Z","timestamp":1735689600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"abstract":"<jats:p>Kaposi\u2019s sarcoma (KS) is a tumor involving blood vessels and lymphatic tissue. It is caused by human herpes virus-8, typically in HIV infection in individuals with AIDS. There are 4 major types of KS including classic, endemic, immunosuppression, and AIDS-related. Endemic KS is unique among the different types as it is associated with patients with HIV-seronegative and can present either as an indolent tumor or as a fast-growing mass. The authors discuss a unique presentation of metastatic, endemic KS in a patient with HIV-negative, non-immunosuppression, which has yet to be described in the United States. A 38-year-old male with a history of same-sex partners, presented with a new oral lesion that had appeared 6 weeks ago. He was negative for human papillomavirus or HIV infection. A computed tomography (CT) scan demonstrated destructive lesions of the hard palate. The specimens obtained from biopsy were consistent with endemic KS. A Positron Emission Tomography \u2013 computed tomography (PET-CT) scan showed widely-metastatic disease. Case reports have described a rare subtype of HIV-seronegative KS in men who have sex with men. However, these are typically-indolent tumors with exclusively-cutaneous manifestation. This is a unique case of aggressive, widely-metastatic endemic KS metastatic in a patient with HIV-negative.<\/jats:p>","DOI":"10.1177\/01455613241307536","type":"journal-article","created":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T23:23:02Z","timestamp":1735773782000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":2,"title":["A Unique Case of Metastatic Oral Kaposi Sarcoma in an HIV-Negative Patient"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-8271-6103","authenticated-orcid":false,"given":"Spencer H.","family":"Short","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head & Neck Surgery, Lehigh Valley Health Network, Allentown, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"McGlone","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head & Neck Surgery, Lehigh Valley Health Network, Allentown, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chetan S.","family":"Nayak","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head & Neck Surgery, Lehigh Valley Health Network, Allentown, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,1,1]]},"reference":[{"key":"bibr1-01455613241307536","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X211066411"},{"key":"bibr2-01455613241307536","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/1818304"},{"key":"bibr3-01455613241307536","doi-asserted-by":"publisher","DOI":"10.1007\/S12105-018-0902-X"},{"key":"bibr4-01455613241307536","doi-asserted-by":"publisher","DOI":"10.1111\/TID.13347"},{"key":"bibr5-01455613241307536","doi-asserted-by":"publisher","DOI":"10.1016\/J.IJOM.2007.04.008"},{"key":"bibr6-01455613241307536","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-017-0270-4"},{"key":"bibr7-01455613241307536","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01696-22"},{"key":"bibr8-01455613241307536","doi-asserted-by":"publisher","DOI":"10.1111\/IJD.14080"},{"key":"bibr9-01455613241307536","doi-asserted-by":"publisher","DOI":"10.1080\/14787210.2023.2247161"},{"key":"bibr10-01455613241307536","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2009.12.006"},{"key":"bibr11-01455613241307536","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15030872"},{"key":"bibr12-01455613241307536","doi-asserted-by":"publisher","DOI":"10.1097\/CCO.0000000000000601"}],"container-title":["Ear, Nose &amp; Throat Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613241307536","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/01455613241307536","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613241307536","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:36:04Z","timestamp":1777401364000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/01455613241307536"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,1]]},"references-count":12,"alternative-id":["10.1177\/01455613241307536"],"URL":"https:\/\/doi.org\/10.1177\/01455613241307536","relation":{},"ISSN":["0145-5613","1942-7522"],"issn-type":[{"value":"0145-5613","type":"print"},{"value":"1942-7522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,1,1]]},"article-number":"01455613241307536"}}