{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,5]],"date-time":"2026-11-05T22:06:40Z","timestamp":1793916400514,"version":"4.8.0"},"reference-count":18,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2025,4,1]],"date-time":"2025-04-01T00:00:00Z","timestamp":1743465600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"abstract":"<jats:p>Acute suppurative thyroiditis (AST) is a rare endocrine emergency, typically of bacterial origin, that can lead to significant morbidity and life-threatening complications. It is far less common than other inflammatory thyroid conditions, such as subacute thyroiditis, and may mimic noninfectious inflammatory disorders. Case 1 describes a 40-year-old man with a 5-day history of anterior neck swelling and odynophagia. Physical examination and imaging confirmed AST with retropharyngeal space involvement. He was treated with broad-spectrum intravenous antibiotics and thyroid abscess aspiration. Case 2 involved a patient with an 11-day history of fever and odynophagia. Imaging, including computed tomography and neck ultrasound, revealed a left thyroid lobe abscess extending into the retropharyngeal space. Further evaluation led to the diagnosis of a fourth branchial cleft cyst and a left pyriform fossa sinus tract. A multidisciplinary approach successfully managed both the acute infection and the underlying anatomical anomaly. Retropharyngeal extension of suppurative thyroiditis is exceedingly rare but signifies a severe disease progression with complex clinical implications. This report highlights the need to consider suppurative thyroiditis in the differential diagnosis of midline cervical infections.<\/jats:p>","DOI":"10.1177\/01455613251331704","type":"journal-article","created":{"date-parts":[[2025,4,2]],"date-time":"2025-04-02T03:04:20Z","timestamp":1743563060000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Acute Suppurative Thyroiditis Extending to Retropharyngeal Space: Report of 2 Cases"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3373-0216","authenticated-orcid":false,"given":"Asimakis D.","family":"Asimakopoulos","sequence":"first","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, Lausanne University Hospital, University of Lausanne, Lausanne, Vaud, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eug\u00e9nie","family":"Delaine","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, H\u00f4pital de Sion, Valais Hospital, Sion, Valais, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avinash","family":"Beharry","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, Lausanne University Hospital, University of Lausanne, Lausanne, Vaud, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Salim","family":"Bouayed","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology, H\u00f4pital de Sion, Valais Hospital, Sion, Valais, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fran\u00e7ois","family":"Gorostidi","sequence":"additional","affiliation":[{"name":"Department of Otorhinolaryngology\u2013Head and Neck Surgery, Lausanne University Hospital, University of Lausanne, Lausanne, Vaud, Switzerland"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,4]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1111\/cen.14440"},{"key":"e_1_3_3_3_2","volume-title":"Werner and Ingbar\u2019s the Thyroid: A Fundamental and Clinical Text","author":"Braverman L","year":"2005","unstructured":"Braverman L, Utiger R, Werner S, Ingbar S. 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