{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:34:03Z","timestamp":1777563243300,"version":"3.51.4"},"reference-count":11,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T00:00:00Z","timestamp":1753401600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>National Institute for Health and Care Excellence (NICE) no longer recommends offering systemic staging for early laryngeal cancer (T1N0 and T2N0). We aim to evaluate (1) whether guidance is being followed in our centre, (2) assess the impact on our patients and (3) perform a cost analysis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>We retrospectively reviewed all laryngeal cases at a major Head and Neck cancer centre between January 01, 2020, and January 01, 2025. The following information was collected for all the patients: neck\/systemic imaging modalities performed on patients, demographics, site of original laryngeal tumour and any metastatic disease detected by systemic imaging. We performed a cost analysis based on methods undertaken by NICE.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>n = 83 patients had laryngeal cancer, n = 30 had T1N0 and T2N0 disease. Systemic imaging found no metastatic disease, n = 2 primary tumours and n = 1 lung infection. Systemic imaging cost \u00a34207.12 and neck imaging cost \u00a312 335.07.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>NICE guidance is not being followed at our centre, with limited benefits.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/01455613251357445","type":"journal-article","created":{"date-parts":[[2025,7,25]],"date-time":"2025-07-25T10:56:42Z","timestamp":1753441002000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Systemic Imaging for Early Laryngeal Cancer: A Single-Centre Review of Guideline Application in Contemporary Clinical Practice"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-8267-1740","authenticated-orcid":false,"given":"Parth Ankur","family":"Tagdiwala","sequence":"first","affiliation":[{"name":"Division of Medicine, University College London Medical School, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sneha","family":"Kanth","sequence":"additional","affiliation":[{"name":"Division of Medicine, University College London Medical School, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Stimpson","sequence":"additional","affiliation":[{"name":"Head and Neck centre, University College London Hospital Trust, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,7,25]]},"reference":[{"key":"e_1_3_3_2_2","unstructured":"DAHNO. National head and neck cancer audit DAHNO fourth annual report NHS digital NHS 2009. Accessed 2025. https:\/\/digital.nhs.uk\/data-and-information\/publications\/statistical\/national-head-and-neck-cancer-audit\/national-head-and-neckcancer-audit-2009-dahno-fifth-annual-report"},{"key":"e_1_3_3_3_2","unstructured":"NICE. Recommendations | Cancer of the upper aerodigestive tract: assessment and management in people aged 16 and over | Guidance (Internet). 2018. www.nice.org.uk. https:\/\/www.nice.org.uk\/guidance\/ng36\/chapter\/Recommendation"},{"key":"e_1_3_3_4_2","unstructured":"National Collaborating Centre for Cancer (Internet). Cancers of the upper aerodigestive tract assessment and management in people aged 16 and over: NICE Guidline 36. Appendices A-G. 2016. Accessed 2025. https:\/\/www.nice.org.uk\/guidance\/ng36\/evidence\/appendices-ag-pdf-2307980270"},{"key":"e_1_3_3_5_2","unstructured":"NHS England. 2020\/2021 National Cost Collection Data Publication (Internet). 2020. Accessed 2025. www.england.nhs.uk. https:\/\/www.england.nhs.uk\/publication\/2020-21-national-cost-collection-data-publication\/"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1111\/odi.13681"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-024-08731-9"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1080\/0284186X.2023.2254482"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.4103\/ijc.IJC_273_18"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-015-3699-1"},{"key":"e_1_3_3_11_2","doi-asserted-by":"publisher","DOI":"10.1378\/chest.06-3096"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.2016.77"}],"container-title":["Ear, Nose &amp; Throat Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613251357445","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/01455613251357445","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613251357445","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:38:52Z","timestamp":1777401532000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/01455613251357445"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,25]]},"references-count":11,"alternative-id":["10.1177\/01455613251357445"],"URL":"https:\/\/doi.org\/10.1177\/01455613251357445","relation":{},"ISSN":["0145-5613","1942-7522"],"issn-type":[{"value":"0145-5613","type":"print"},{"value":"1942-7522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,25]]},"article-number":"01455613251357445"}}