{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:34:27Z","timestamp":1777563267849,"version":"3.51.4"},"reference-count":23,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T00:00:00Z","timestamp":1753920000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>To determine whether the presence of vocal cord paralysis (VCP) has an impact on overall survival (OS) and quality of life in patients diagnosed with extralaryngeal malignancies.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>\n                      This was a retrospective chart review of patients at a quaternary medical center from 2007 to 2022. Information on demographics, cancer diagnosis, treatment, and intervention for VCP was collected. Patients were identified using\n                      <jats:italic toggle=\"yes\">International Classification of Diseases<\/jats:italic>\n                      (ICD)-9 and ICD-10 codes for various malignancies and VCP and cross-referenced. Patients with both VCP and extralaryngeal malignancy were included, while those without malignancy, with laryngeal cancer, VCP unrelated to cancer, or without laryngoscopy-confirmed VCP were excluded. No validated instruments to measure quality of life were utilized.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      A total of 346 patients with VCP related to 52 distinct, extralaryngeal malignancies were identified. Mean OS was 97.35 months. Mean OS for those diagnosed with early (stage 1 or 2) cancers was 101.48 months and 79.88 months for late (stage 3 or 4) cancers (\n                      <jats:italic toggle=\"yes\">P<\/jats:italic>\n                      = &lt;.0001). Many of our patients (56.6%) did not receive VCP treatment.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion:<\/jats:title>\n                    <jats:p>Treatment for cancer patients with VCP poses a unique challenge with a multitude of factors affecting management. However, given that patients survive months after VCP diagnosis, they should be offered treatments that carry low morbidity and increase their quality of life.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/01455613251360134","type":"journal-article","created":{"date-parts":[[2025,7,31]],"date-time":"2025-07-31T12:16:58Z","timestamp":1753964218000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Life Expectancy in Patients Diagnosed with Extralaryngeal Malignancies and Vocal Cord Paralysis"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1254-5169","authenticated-orcid":false,"given":"Danae","family":"Alexandrou","sequence":"first","affiliation":[{"name":"Stritch School of Medicine, Loyola University Chicago, Maywood, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Veronica","family":"Drozdowski-Nuccio","sequence":"additional","affiliation":[{"name":"Loyola University Medical Center, Maywood, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kayeromi","family":"Gomez","sequence":"additional","affiliation":[{"name":"Loyola University Medical Center, Maywood, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Steven","family":"Charous","sequence":"additional","affiliation":[{"name":"Loyola University Medical Center, Maywood, IL, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,7,31]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1186\/s13244-019-0786-7"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2008.09.010"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.5681\/jcvtr.2014.009"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12070-012-0574-x"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.1159\/000099226"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdq733"},{"key":"e_1_3_3_8_2","doi-asserted-by":"publisher","DOI":"10.1016\/0959-8049(95)00296-0"},{"key":"e_1_3_3_9_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1993.11.3.570"},{"key":"e_1_3_3_10_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1445-1433.2001.02233.x"},{"issue":"1","key":"e_1_3_3_11_2","first-page":"41","article-title":"Medialization thyroplasty for unilateral vocal cord paralysis secondary to advanced extralaryngeal malignant disease: review of operative morbidity and patient life expectancy","volume":"41","author":"Morrissey AT","year":"2012","unstructured":"Morrissey AT, O\u2019Connell DA, Allegretto M. Medialization thyroplasty for unilateral vocal cord paralysis secondary to advanced extralaryngeal malignant disease: review of operative morbidity and patient life expectancy. J Otolaryngol Head Neck Surg. 2012;41(1):41-45.","journal-title":"J Otolaryngol Head Neck Surg"},{"key":"e_1_3_3_12_2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2273.2002.00601.x"},{"key":"e_1_3_3_13_2","doi-asserted-by":"publisher","DOI":"10.1177\/000348940211100802"},{"key":"e_1_3_3_14_2","unstructured":"State of Lung Cancer 2022 Report. American Lung Association; 2022. Accessed April 2022. https:\/\/www.lung.org\/getmedia\/647c433b-4cbc-4be6-9312-2fa9a449d489\/solc-2022-print-report.pdf"},{"key":"e_1_3_3_15_2","volume-title":"Cancer Facts & Figures 2023","author":"American Cancer Society","year":"2023","unstructured":"American Cancer Society. Cancer Facts & Figures 2023. 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