{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T01:52:33Z","timestamp":1787881953909,"version":"build-2784847793"},"reference-count":24,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T00:00:00Z","timestamp":1759968000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"name":"Neurent Medical"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"abstract":"<jats:sec>\n                    <jats:title>Objective:<\/jats:title>\n                    <jats:p>A person\u2019s quality of life can be deeply impacted by chronic rhinitis. We report 2-year outcomes in patients after treatment using a novel, multipoint, impedance-controlled, radiofrequency ablation device.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods:<\/jats:title>\n                    <jats:p>A prospective, multicenter, single-arm clinical study of posterior nasal nerve ablation in adults with chronic rhinitis. Efficacy assessments included the reflective total nasal symptom score (rTNSS), postnasal drip, cough, Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7), nasal obstruction symptom evaluation (NOSE), and mini-Rhinoconjunctivitis Quality of Life Questionnaire (mini-RQLQ).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results:<\/jats:title>\n                    <jats:p>\n                      Seventy-five of 80 (94%) participants completed 2-year follow-up. Statistically significant improvements were observed in rhinitis symptoms, postnasal drip, cough, ear symptoms, and quality of life as evidenced by the mean change in rTNSS (\u22124.3), postnasal drip (\u22120.9), cough (\u22120.7), ETDQ-7 (\u22121.1), NOSE (\u221231.7), and mini-RQLQ (\u22121.7;\n                      <jats:italic>P<\/jats:italic>\n                      \u2009&lt;\u2009.0001 for all). Allergic and nonallergic rhinitis subgroups demonstrated similar, significant improvement. No serious related adverse events were reported between the 9-month and 2-year follow-ups.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions:<\/jats:title>\n                    <jats:p>The data demonstrate consistent long-term efficacy and safety of a multipoint, impedance-controlled, radiofrequency ablation device for the treatment of chronic rhinitis. Significant improvements were observed in rhinitis symptoms, postnasal drip, cough, ear symptoms, and quality of life through 2-year follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Study Registration:<\/jats:title>\n                    <jats:p>\n                      <jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" ext-link-type=\"uri\" xlink:href=\"https:\/\/www.clinicaltrials.gov\">www.clinicaltrials.gov<\/jats:ext-link>\n                      . Unique identifier NCT05591989.\n                    <\/jats:p>\n                  <\/jats:sec>","DOI":"10.1177\/01455613251382759","type":"journal-article","created":{"date-parts":[[2025,10,9]],"date-time":"2025-10-09T14:00:47Z","timestamp":1760018447000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":4,"title":["Two-Year Clinical Outcomes After Multipoint Impedance-Controlled Radiofrequency Ablation of the Posterior Nasal Nerve for Treatment of Chronic Rhinitis"],"prefix":"10.1177","author":[{"given":"David M.","family":"Yen","sequence":"first","affiliation":[{"name":"Specialty Physician Associates, Bethlehem, PA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Greg E.","family":"Davis","sequence":"additional","affiliation":[{"name":"Proliance Surgeons, Seattle and Puyallup, WA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5151-5731","authenticated-orcid":false,"given":"Randall A.","family":"Ow","sequence":"additional","affiliation":[{"name":"Sacramento Ear, Nose, and Throat, Roseville, CA, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3751-764X","authenticated-orcid":false,"given":"Ellen M.","family":"O\u2019Malley","sequence":"additional","affiliation":[{"name":"O\u2019Malley Medical Communications, LLC, Victoria, MN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anthony G.","family":"Del Signore","sequence":"additional","affiliation":[{"name":"Mount Sinai Hospital System, New York, NY, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2025,10,9]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2017.09.002"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.2500\/aap.2012.33.3603"},{"key":"e_1_3_3_4_2","doi-asserted-by":"publisher","DOI":"10.2500\/ajra.2012.26.3799"},{"key":"e_1_3_3_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.otc.2018.05.010"},{"key":"e_1_3_3_6_2","doi-asserted-by":"publisher","DOI":"10.23822\/EurAnnACI.1764-1489.268"},{"key":"e_1_3_3_7_2","doi-asserted-by":"publisher","DOI":"10.1002\/lio2.1040"},{"issue":"3","key":"e_1_3_3_8_2","article-title":"Long-term outcomes following impedance-controlled radiofrequency ablation for the treatment of chronic rhinitis","volume":"9","author":"Reh DD","year":"2024","unstructured":"Reh DD, Lay K, Davis G, et al Long-term outcomes following impedance-controlled radiofrequency ablation for the treatment of chronic rhinitis. 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