{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T15:36:24Z","timestamp":1777563384309,"version":"3.51.4"},"reference-count":14,"publisher":"SAGE Publications","license":[{"start":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T00:00:00Z","timestamp":1765843200000},"content-version":"vor","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"},{"start":{"date-parts":[[2025,12,16]],"date-time":"2025-12-16T00:00:00Z","timestamp":1765843200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ear Nose Throat J"],"abstract":"<jats:p>Myeloid sarcoma (MS) is a rare extramedullary myeloid malignancy that may occur with or without bone marrow involvement. Nasopharyngeal cases are exceedingly rare, making diagnosis challenging, and most reported cases present with local symptoms caused by a bulky mass. We report a 64-year-old man with a history of myelodysplastic syndrome who presented with cervical lymphadenopathy without any nasal or otologic symptoms. Endoscopic examination revealed a small, smooth bulging lesion on the left nasopharyngeal wall. Contrast-enhanced computed tomography demonstrated a polypoid mass with bilateral cervical lymphadenopathy. Histopathological and immunohistochemical analyses confirmed MS. Bone marrow evaluation revealed leukemic transformation to acute myeloid leukemia. The patient received combination chemotherapy with venetoclax and azacitidine but died 2\u2009months after treatment initiation. This asymptomatic presentation emphasizes the diagnostic difficulty of MS arising in atypical anatomical locations. Early tissue biopsy and prompt hematologic assessment are essential for accurate diagnosis and timely management. Nasopharyngeal MS should be considered in the differential diagnosis of nasopharyngeal masses, particularly in patients with a history of myelodysplastic or myeloproliferative disorders.<\/jats:p>","DOI":"10.1177\/01455613251408029","type":"journal-article","created":{"date-parts":[[2025,12,17]],"date-time":"2025-12-17T06:12:46Z","timestamp":1765951966000},"update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":0,"title":["Asymptomatic Nasopharyngeal Myeloid Sarcoma Presenting With Cervical Lymphadenopathy: A Case Report"],"prefix":"10.1177","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5371-3598","authenticated-orcid":false,"given":"Eun Kyung","family":"Jung","sequence":"first","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9288-5368","authenticated-orcid":false,"given":"Dong Hoon","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Otolaryngology\u2014Head and Neck Surgery, Chonnam National University Medical School and Chonnam National University Hwasun Hospital, Korea"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,12,16]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.1038\/sj.leu.2404491"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.clml.2017.02.027"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19810915)48:6<1426::AID-CNCR2820480626>3.0.CO;2-G"},{"issue":"4","key":"e_1_3_2_5_2","first-page":"265","article-title":"Granulocytic sarcoma: a systematic review","volume":"3","author":"Yilmaz AF","year":"2013","unstructured":"Yilmaz AF, Saydam G, Sahin F, Baran Y. Granulocytic sarcoma: a systematic review. Am J Blood Res. 2013;3(4):265-270.","journal-title":"Am J Blood Res"},{"issue":"3","key":"e_1_3_2_6_2","first-page":"83","article-title":"WHO classification of tumours of haematopoietic and lymphoid tissues in 2008: an overview","volume":"102","author":"Sabattini E","year":"2010","unstructured":"Sabattini E, Bacci F, Sagramoso C, Pileri S. WHO classification of tumours of haematopoietic and lymphoid tissues in 2008: an overview. Pathologica. 2010;102(3):83-87.","journal-title":"Pathologica"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1097\/00000441-189308000-00003"},{"key":"e_1_3_2_8_2","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.1131"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.4103\/ijpm.ijpm_791_21"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2022-251681"},{"key":"e_1_3_2_11_2","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2013.238"},{"key":"e_1_3_2_12_2","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23691"},{"key":"e_1_3_2_13_2","doi-asserted-by":"publisher","DOI":"10.1080\/10428190600967196"},{"key":"e_1_3_2_14_2","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.1995.13.7.1800"},{"key":"e_1_3_2_15_2","doi-asserted-by":"publisher","DOI":"10.1007\/s12672-024-01068-z"}],"container-title":["Ear, Nose &amp; Throat Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613251408029","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/01455613251408029","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01455613251408029","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T18:39:19Z","timestamp":1777401559000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/01455613251408029"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,16]]},"references-count":14,"alternative-id":["10.1177\/01455613251408029"],"URL":"https:\/\/doi.org\/10.1177\/01455613251408029","relation":{},"ISSN":["0145-5613","1942-7522"],"issn-type":[{"value":"0145-5613","type":"print"},{"value":"1942-7522","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,16]]},"article-number":"01455613251408029"}}