{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T16:06:12Z","timestamp":1777910772606,"version":"3.51.4"},"reference-count":35,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2012,4,16]],"date-time":"2012-04-16T00:00:00Z","timestamp":1334534400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Diabetes Educ"],"published-print":{"date-parts":[[2012,5]]},"abstract":"<jats:p>Purpose<\/jats:p>\n                  <jats:p>The purpose of this study is to assess the relationship between magnitude of weight loss and improvement in percentage A1C (A1C%) among overweight and obese patients with type 2 diabetes mellitus (DM) undergoing weight reduction.<\/jats:p>\n                  <jats:p>Methods<\/jats:p>\n                  <jats:p>Case records of patients enrolled in 2 university-based weight management programs were reviewed. Patients were sampled if they had a diagnosis of DM and had at least 1 documented A1C% reduction from their baseline value. Weight loss treatment was individualized and consisted of a calorie-restricted diet, a behavior modification plan, and a plan for increasing physical activity. Patient weights were measured at bimonthly visits. A1C% was measured every 3 months.<\/jats:p>\n                  <jats:p>Results<\/jats:p>\n                  <jats:p>\n                    Seventy-two patients formed the study cohort. Mean baseline body mass index was 35.1 kg\/m\n                    <jats:sup>2<\/jats:sup>\n                    , mean age was 52.6 years, and 59% were males. Mean starting A1C% was 8.6. Patients achieved significant mean weight loss (10.7 kg) at study exit. Weight loss of 6.5 kg (4.5% of baseline body weight), 12.2 kg (8.7%), and 15.9 kg (10.3%) was required to reduce A1C% by 0.5, 1, and 1.5, respectively, and it took a mean of 5.6, 8.7, and 10.1 months, respectively, to achieve this. After adjustment for antidiabetic medication intake, for every 10% weight loss, the predicted reduction in A1C% was 0.81.\n                  <\/jats:p>\n                  <jats:p>Conclusions<\/jats:p>\n                  <jats:p>Intentional weight loss of 10% can potentially decrease A1C% by 0.81 among patients with type 2 DM. This finding may be clinically useful in encouraging and counseling a patient attempting weight loss.<\/jats:p>","DOI":"10.1177\/0145721712443293","type":"journal-article","created":{"date-parts":[[2012,4,17]],"date-time":"2012-04-17T00:42:10Z","timestamp":1334623330000},"page":"417-426","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":36,"title":["Association Between Glycosylated Hemoglobin and Intentional Weight Loss in Overweight and Obese Patients With Type 2 Diabetes Mellitus"],"prefix":"10.1177","volume":"38","author":[{"given":"Ghanshyam Palamaner Subash","family":"Shantha","sequence":"first","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (Dr Shantha, Dr Kumar)"},{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, and George Washington University School of Public Health and Health Services, Washington, DC (Dr Kahan)"},{"name":"Johns Hopkins Weight Management Center, Department of Health, Behavior & Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, (Dr Cheskin)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita Ashok","family":"Kumar","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (Dr Shantha, Dr Kumar)"},{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, and George Washington University School of Public Health and Health Services, Washington, DC (Dr Kahan)"},{"name":"Johns Hopkins Weight Management Center, Department of Health, Behavior & Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, (Dr Cheskin)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Scott","family":"Kahan","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (Dr Shantha, Dr Kumar)"},{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, and George Washington University School of Public Health and Health Services, Washington, DC (Dr Kahan)"},{"name":"Johns Hopkins Weight Management Center, Department of Health, Behavior & Society, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, (Dr Cheskin)"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lawrence J.","family":"Cheskin","sequence":"additional","affiliation":[{"name":"Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland (Dr Shantha, Dr Kumar)"},{"name":"Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland, and George Washington University School of Public Health and Health Services, Washington, DC (Dr Kahan)"},{"name":"Johns Hopkins Weight Management Center, Department of Health, Behavior & Society, Johns Hopkins Bloomberg 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