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Building on evidence that at least some students drink in response to negative experiences, we considered the possibility that positive moods would moderate college student negative mood\u2014drinking relationships. Using a Web-based daily process study of 118 (57% women) undergraduate student drinkers, the authors reveal that positive moods indeed buffer the effects of negative moods on student drinking, depending on the mood and drinking context. Furthermore, the buffering of ashamed mood appears to explain the buffering of other negative moods. 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