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The effects of semi\u2010solid nutrients on gastroesophageal reflux, intragastric distribution, and gastric emptying were evaluated. <jats:italic>Methods:<\/jats:italic> Semi\u2010solid nutrients were prepared by liquid nutrients mixed with agar at the concentration of 0.5%. The distribution of the administered radiolabeled liquid and semi\u2010solid nutrients was monitored by a scintillation camera for 15 post\u2010PEG patients. The percentage of esophageal reflux, the distribution of the proximal and distal stomach, and the gastric emptying time were evaluated. <jats:italic>Results:<\/jats:italic> The percentage of gastroesophageal reflux was significantly decreased in semi\u2010solid nutrients (0.82 \u00b1 1.27%) compared with liquid nutrients (3.75 \u00b1 4.25%), whereas the gastric emptying time was not different. The distribution of semi\u2010solid nutrients was not different from liquid nutrients in the early phase, whereas higher retention of liquid nutrients in the proximal stomach was observed in the late phase. <jats:italic>Conclusions:<\/jats:italic> Gastroesophageal reflux was significantly inhibited by semi\u2010solid nutrients. One of the mechanisms of the inhibition is considered to be an improvement in the transition from the proximal to distal stomach in semi\u2010solid nutrients.<\/jats:p>","DOI":"10.1177\/0148607108327045","type":"journal-article","created":{"date-parts":[[2009,6,1]],"date-time":"2009-06-01T21:35:02Z","timestamp":1243892102000},"page":"513-519","source":"Crossref","is-referenced-by-count":46,"title":["Inhibition of Gastroesophageal Reflux by Semi\u2010solid Nutrients in Patients With Percutaneous Endoscopic 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