{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T12:58:56Z","timestamp":1784638736364,"version":"3.55.0"},"reference-count":26,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"},{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"http:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[2017,5]]},"abstract":"<jats:p>Fish oil\u2013based lipid emulsions (FOLEs) have been used to treat cholestasis in children with intestinal failure\u2013associated liver disease (IFALD). When FOLEs are dosed at 1 g\/kg\/d, essential fatty acid (EFA) deficiency typically does not occur. We describe the clinical course of a severely malnourished parenteral nutrition\u2013dependent infant with IFALD. Baseline EFA panels were normal upon starting FOLE at 1 g\/kg\/d. Despite biochemical improvement in IFALD, weight velocity was below target and biochemical EFA status worsened, even after correction for other factors affecting weight. The FOLE dose was increased to 1.5 g\/kg\/d, resulting in improvement of weight velocity and EFA status. This suggests that in severely malnourished infants being treated for IFALD, higher doses of FOLE may be required for adequate growth and to prevent EFA deficiency.<\/jats:p>","DOI":"10.1177\/0148607116661031","type":"journal-article","created":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T23:14:45Z","timestamp":1470093285000},"page":"667-671","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":12,"title":["Higher Doses of Fish Oil\u2013Based Lipid Emulsions Used to Treat Inadequate Weight Gain and Rising Triene:Tetraene Ratio in a Severely Malnourished Infant With Intestinal Failure\u2013Associated Liver Disease"],"prefix":"10.1002","volume":"41","author":[{"given":"Mary","family":"Riedy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brittany","family":"DePaula","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Puder","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathleen M.","family":"Gura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin A.","family":"Sztam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2008.01.005"},{"key":"e_1_2_6_3_1","first-page":"247","volume-title":"Clinical Management of Intestinal Failure","author":"Diamond IR"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.12.021"},{"key":"e_1_2_6_5_1","first-page":"263","volume-title":"Clinical Management of Intestinal Failure","author":"Fallon EM"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.3945\/an.113.004770"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2010.80"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e3181bbf51e"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/70.3.405"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.2009.173062"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2005-2662"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-2248"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clnu.2005.05.020"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2011.09.061"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.plefa.2009.05.020"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2010.09.072"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607114527772"},{"key":"e_1_2_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpedsurg.2013.03.040"},{"key":"e_1_2_6_19_1","doi-asserted-by":"publisher","DOI":"10.1203\/01.PDR.0000153672.43030.75"},{"key":"e_1_2_6_20_1","doi-asserted-by":"publisher","DOI":"10.1159\/000358267"},{"key":"e_1_2_6_21_1","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0b013e318182c8f6"},{"key":"e_1_2_6_22_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.110.008557"},{"key":"e_1_2_6_23_1","article-title":"Low\u2010dose intravenous soybean oil emulsion for prevention of cholestasis in preterm neonates","author":"Levit OL","year":"2014","journal-title":"J Parenter Enteral Nutr"},{"key":"e_1_2_6_24_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607113495416"},{"key":"e_1_2_6_25_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026683214681"},{"key":"e_1_2_6_26_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-005-3068-9"},{"key":"e_1_2_6_27_1","doi-asserted-by":"publisher","DOI":"10.1002\/j.1536-4801.2005.tb00011.x"}],"container-title":["Journal of Parenteral and Enteral Nutrition"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/0148607116661031","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/0148607116661031","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0148607116661031","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T10:13:34Z","timestamp":1760868814000},"score":1,"resource":{"primary":{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0148607116661031"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["10.1177\/0148607116661031"],"URL":"https:\/\/doi.org\/10.1177\/0148607116661031","archive":["Portico"],"relation":{},"ISSN":["0148-6071","1941-2444"],"issn-type":[{"value":"0148-6071","type":"print"},{"value":"1941-2444","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8]]}}}