{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T16:11:51Z","timestamp":1760631111607,"version":"build-2065373602"},"reference-count":19,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1978,11,1]],"date-time":"1978-11-01T00:00:00Z","timestamp":278726400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[1978,11]]},"abstract":"<jats:p>Over a 7 1\/2\u2010year period, 94 cancer patients presenting considerable operative risk were managed by total parenteral nutrition (TPN). All were nutritionally depleted, had obstruction to the gastrointestinal tract or had postoperative complications such as enterocutaneous fistulas, evisceration or intra\u2010abdominal sepsis, which left TPN as the only means of achieving anabolism. When TPN was started preoperatively and continued postoperatively (28 patients\u2013\u2010Group 1), no deaths or significant complications occurred. When TPN was first started after life\u2010threatening complications had occurred (58 patients\u2013\u2010Group 2), the mortality was 17.2%, so that a high incidence of recovery was achieved. When TPN was used in inoperable cachectic patients (8 patients\u2013\u2010Group 3) to enable them to tolerate radiotherapy or chemotherapy, the mortality was 37.5%. This latter group is small, but TPN is worthwhile in selected patients where significant palliation and improvement in the quality of life can occur. With careful technique, risk of sepsis with TPN was no greater than in noncancer patients.<\/jats:p>","DOI":"10.1177\/014860717800200509","type":"journal-article","created":{"date-parts":[[2017,1,17]],"date-time":"2017-01-17T02:48:27Z","timestamp":1484621307000},"page":"671-675","source":"Crossref","is-referenced-by-count":0,"title":["Specialized Nutritional Support and Cancer"],"prefix":"10.1002","volume":"2","author":[{"given":"Mervyn","family":"Deitel","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Vasic","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1978,11]]},"reference":[{"key":"e_1_2_1_2_1","first-page":"15","article-title":"The delayed hypersensitivity response: Clinical application in surgery.","volume":"20","author":"Pietsch JB","year":"1977","journal-title":"Can J Surg"},{"key":"e_1_2_1_3_1","first-page":"334","article-title":"Major gastrointestinal problems after radiotherapy: Management and nutritional considerations.","volume":"62","author":"Deitel M","year":"1977","journal-title":"Int Surg"},{"key":"e_1_2_1_4_1","first-page":"670","article-title":"A system of intravenous hyperalimentation.","volume":"58","author":"Deitel M","year":"1973","journal-title":"Int Surg"},{"key":"e_1_2_1_5_1","first-page":"152","article-title":"Total nutrition by peripheral vein\u2014the lipid system.","volume":"111","author":"Deitel M","year":"1974","journal-title":"Can Med Assoc J"},{"key":"e_1_2_1_6_1","first-page":"505","article-title":"Nutritional management of external gastrointestinal fistulas.","volume":"19","author":"Deitel M","year":"1976","journal-title":"Can J Surg"},{"key":"e_1_2_1_7_1","first-page":"175","article-title":"A crystalline amino acid solution for total parenteral nutrition.","volume":"30","author":"Deitel M","year":"1977","journal-title":"Can J Hosp Pharm"},{"key":"e_1_2_1_8_1","first-page":"531","article-title":"Growth of common bacteria and Candida albicans in 10% soybean emulsion.","volume":"18","author":"Deitel M","year":"1975","journal-title":"Can J Surg"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1972.03200130051010"},{"key":"e_1_2_1_10_1","first-page":"60","article-title":"Preparation of solutions for hyperalimentation.","volume":"25","author":"Sauve Sr F","year":"1972","journal-title":"Can J Hosp Pharm"},{"key":"e_1_2_1_11_1","first-page":"471","article-title":"Elemental diets in management of clinical nutritional problems.","volume":"29","author":"Deitel M","year":"1974","journal-title":"Mod Med Can"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(74)90038-9"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(75)90293-7"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-79-4-545"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197607000-00010"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197702)39:2<609::AID-CNCR2820390236>3.0.CO;2-0"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(75)90109-2"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(71)90095-X"},{"key":"e_1_2_1_19_1","first-page":"577","article-title":"Intravenous hyperalimentation without sepsis.","volume":"136","author":"Sanderson I","year":"1973","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_20_1","first-page":"377","article-title":"Intravenous hyperalimentation in patients with potential sepsis.","volume":"138","author":"Copeland EM","year":"1974","journal-title":"Surg Gynecol Obstet"}],"container-title":["Journal of Parenteral and Enteral Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/014860717800200509","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T15:34:14Z","timestamp":1760628854000},"score":1,"resource":{"primary":{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/10.1177\/014860717800200509"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1978,11]]},"references-count":19,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1978,11]]}},"alternative-id":["10.1177\/014860717800200509"],"URL":"https:\/\/doi.org\/10.1177\/014860717800200509","archive":["Portico"],"relation":{},"ISSN":["0148-6071","1941-2444"],"issn-type":[{"type":"print","value":"0148-6071"},{"type":"electronic","value":"1941-2444"}],"subject":[],"published":{"date-parts":[[1978,11]]}}}