{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T10:42:11Z","timestamp":1779100931494,"version":"3.51.4"},"reference-count":23,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1984,11,1]],"date-time":"1984-11-01T00:00:00Z","timestamp":468115200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[1984,11]]},"abstract":"<jats:p>Two patients requiring total parenteral nutrition for 34 and 39 months, had plasma and urinary carnitine assays and plasma lipid assays performed before and during intravenous administration of 400 mg (2500 \u03bcmol) of L\u2010carnitine for 7 days, followed by 40 mg (240 \u03bcmol) daily continuously. One patient had generalized lethargy and weakness which resolved within the first 5 days of carnitine administration. The plasma\u2010free carnitine levels in this patient rose significantly. The other patient was asymptomatic and while there was no significant change in the plasma\u2010free carnitine levels during carnitine administration, this patient remained in positive carnitine balance throughout the study. There were no significant changes in plasma lipid levels in either patient. In adult patients requiring long\u2010term total parenteral nutrition who are otherwise normal, intravenous L\u2010carnitine may be required to supplement the patients endogenous carnitine production. <jats:italic>(Journal of Parenteral and Enteral Nutrition<\/jats:italic> 8 :717\u2013719,1984)<\/jats:p>","DOI":"10.1177\/0148607184008006717","type":"journal-article","created":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T19:51:26Z","timestamp":1210794686000},"page":"717-719","source":"Crossref","is-referenced-by-count":14,"title":["Carnitine Balance and Effects of Intravenous L\u2010Carnitine in Two Patients Receiving Long\u2010Term Total Parenteral Nutrition"],"prefix":"10.1002","volume":"8","author":[{"given":"L.I.G.","family":"Worthley","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.C.","family":"Fishlock","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.M.","family":"Snoswell","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1984,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"crossref","first-page":"832","DOI":"10.1016\/S0021-9258(19)45682-2","article-title":"Carnitine palmityltransferase: location of two enzymatic activities in rat liver mitochondria","volume":"247","author":"Hoppel CL","year":"1972","journal-title":"J Biol 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