{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:36:47Z","timestamp":1760888207967,"version":"build-2065373602"},"reference-count":14,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1985,5,1]],"date-time":"1985-05-01T00:00:00Z","timestamp":483753600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[1985,5]]},"abstract":"<jats:p>Nutritional status was evaluated on 210 occasions in 90 pediatric oncology inpatients during a 7\u2010month period; 39 had solid tumors and 51 leukemia. Ages ranged from 3 months to 20 yr. Nutritional parameters were defined as normal, \u201cat risk,\u201d or \u201cprobably malnourished.\u201d Fifty\u2010seven and 29% of assessments revealed at least one parameter \u201cat risk\u201d or \u201cprobably malnourished,\u201d respectively. Prognosis was negatively related to the number of abnormal nutritional parameters. Serum albumin was most frequently abnormal. However, on most occasions, hypoalbuminemia was associated with weight\/height, arm muscle area, and triceps skinfold measurements in the normal range. In order to further identify determinants of serum albumin, we analyzed dietary, chemotherapy, and temperature data in 10 prospectively studied leukemia patients, half of whom received parenteral nutrition. In these patients there was little relationship of serum albumin to chemotherapy or dietary intake. In all of these patients, especially those receiving total parenteral nutrition, low serum albumin was highly associated with fever <jats:italic>(p<\/jats:italic> &lt; 0.0005). We concluded that febrile illness is an important determinant of abnormal serum albumin concentrations. In pediatric cancer patients, abnormal serum albumin may more often reflect the acute metabolic response to fever and infection than depletion of body mass. <jats:italic>(Journal of Parenteral and Enteral Nutrition<\/jats:italic> <jats:bold>9:<\/jats:bold>303\u2013306, 1985)<\/jats:p>","DOI":"10.1177\/0148607185009003303","type":"journal-article","created":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T19:51:26Z","timestamp":1210794686000},"page":"303-306","source":"Crossref","is-referenced-by-count":41,"title":["Significance of Hypoalbuminemia in Pediatric Oncology Patients\u2014 Malnutrition or Infection?"],"prefix":"10.1002","volume":"9","author":[{"given":"Russell J.","family":"Merritt","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maryse","family":"Kalsch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorraine Davis","family":"Roux","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Judith","family":"Ashley\u2010Mills","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stuart S.","family":"Siegel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1985,5]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/pir.5-7-195"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/014860717700100101"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"1320","DOI":"10.1093\/ajcn\/32.6.1320","article-title":"Nutritional survey of hospitalized pediatric patients","volume":"32","author":"Merritt RJ","year":"1979","journal-title":"Am J Clin Nutr"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1002\/mpo.2950110213"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197905)43:5 <2030::AID-CNCR2820430711>3.0.CO;2-S"},{"key":"e_1_2_1_7_1","first-page":"1107","article-title":"A study of the nutritional status of pediatric cancer patients","volume":"135","author":"Donaldson SS","year":"1981","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198008000-00010"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1753-4887.1981.tb06765.x"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(71)90375-8"},{"key":"e_1_2_1_11_1","first-page":"21","article-title":"Iatrogenic kwashiorkor in infants","volume":"135","author":"Sinatra FR","year":"1981","journal-title":"Am J Dis Child"},{"key":"e_1_2_1_12_1","doi-asserted-by":"crossref","first-page":"1148","DOI":"10.1093\/ajcn\/28.10.1148","article-title":"Cellular immunity in semistarved states in hospitalized adults","volume":"28","author":"Bistrian BR","year":"1975","journal-title":"Am J Clin Nutr"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198019250-00004"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/014860718100500170"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/ajcn\/34.10.2013"}],"container-title":["Journal of Parenteral and Enteral Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0148607185009003303","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T16:02:28Z","timestamp":1760630548000},"score":1,"resource":{"primary":{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0148607185009003303"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1985,5]]},"references-count":14,"journal-issue":{"issue":"3","published-print":{"date-parts":[[1985,5]]}},"alternative-id":["10.1177\/0148607185009003303"],"URL":"https:\/\/doi.org\/10.1177\/0148607185009003303","archive":["Portico"],"relation":{},"ISSN":["0148-6071","1941-2444"],"issn-type":[{"type":"print","value":"0148-6071"},{"type":"electronic","value":"1941-2444"}],"subject":[],"published":{"date-parts":[[1985,5]]}}}