{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:50:54Z","timestamp":1760982654178,"version":"build-2065373602"},"reference-count":38,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[1986,3,1]],"date-time":"1986-03-01T00:00:00Z","timestamp":510019200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[1986,3]]},"abstract":"<jats:p>In order to prevent essential fatty acid (EFA) deficiency induced by fat\u2010free total parenteral nutrition (TPN), 10 infants on TPN were rubbed three times daily for 20 days using oenethera oil (80% EFA). Total EFA amount provided cutaneously was 1900 mg\/kg\/d. Plasma and red blood cells phospholipids were determined on days 1 and 20 in these 10 treated and six untreated infants on TPN and compared with those of normal control infants. On day 1, plasma nonessential FA including 20:3 n\u20109(p &lt; 0.01) were increased in both TPN groups while 18:2 n\u20106 and and 18:3 n\u20103 (p &lt; 0.001 and p &lt; 0.01) were decreased. On the 20th day, EFA deficiency had worsened with a decrease in plasma level of 20:4 n\u20106 (p &lt; 0.02) and a higher than normal triene\/tetraene ratio : 3.4\u00b11.1 and 2.3\u00b10.6 us 0.1\u00b10.1 (<jats:italic>p<\/jats:italic> &lt; 0.02). As for red blood cells phospholipids, 16:0 was increased and 18:2 n\u20106 and 20:3 n\u20106 were decreased (p &lt; 0.05) on day 1. On day 20, these FA were more abnormal while 20:3 n\u20109 became significantly increased (p &lt; 0.05). No difference was observed between the TPN groups at any time. These results show that cutaneous application of large amounts of EFA\u2010rich oil is unable to prevent or cure TPN induced EFA deficiency. <jats:italic>(Journal of Parenteral and Enteral Nutrition<\/jats:italic> 10:216\u2013219, 1986)<\/jats:p>","DOI":"10.1177\/0148607186010002216","type":"journal-article","created":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T19:51:26Z","timestamp":1210794686000},"page":"216-219","source":"Crossref","is-referenced-by-count":7,"title":["Plasma and Erythrocyte Essential Fatty Acids during Total Parenteral Nutrition in Infants: Effects of a Cutaneous 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