{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,17]],"date-time":"2025-10-17T00:33:50Z","timestamp":1760661230033,"version":"build-2065373602"},"reference-count":24,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1986,9,1]],"date-time":"1986-09-01T00:00:00Z","timestamp":525916800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[1986,9]]},"abstract":"<jats:p>Contaminated enteral nutrient solution (ENS) was used to assess the risks of intestinal colonization and invasive sepsis using normal mice. Dilute Osmolite containing 10<jats:sup>6<\/jats:sup> Group B Streptococci\/ml given for 2 to 10 consecutive days resulted in the detection of organisms by rectal washing sampling and in the recovery of 10<jats:sup>3<\/jats:sup> to 10<jats:sup>4<\/jats:sup> organisms from the cecum, large intestine, and rectum. Only 10<jats:sup>1<\/jats:sup> organisms survived in the small intestine. Colonization, or the persistence of organisms for 10 days after exposure, was produced after 2 days of ingestion in 44% of animals and in 100% after exposure for 5 days. There were 39 septic deaths. During the 7\u2010day ingestion interval 15 died and 24 died within 10 days after exposure. The risk of sepsis was highest for young mice. Ways to minimize bacterial contamination of ENS intended for administration to patients are discussed. (<jats:italic>Journal of Parenteral and Enteral Nutrition<\/jats:italic> <jats:bold>10:<\/jats:bold> 503\u2013507, 1986)<\/jats:p>","DOI":"10.1177\/0148607186010005503","type":"journal-article","created":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T19:51:26Z","timestamp":1210794686000},"page":"503-507","source":"Crossref","is-referenced-by-count":6,"title":["Bacterial Contamination of Enteral Nutrient Solutions: Intestinal Colonization and Sepsis in Mice after Ingestion"],"prefix":"10.1002","volume":"10","author":[{"given":"Richard A.","family":"Van Enk","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dolores","family":"Furtado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1986,9]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.282.6268.973"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607184008002113"},{"key":"e_1_2_1_4_1","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1542\/peds.63.2.232","article-title":"Environmental contamination of continuous drip feedings","volume":"63","author":"Schreiner RL","year":"1979","journal-title":"Pediatrics"},{"key":"e_1_2_1_5_1","first-page":"27","volume-title":"Report of the Ross Workshop on Contamination of Enteral Feeding Products During Clinical Usage","author":"Beyer PL","year":"1983"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607182006003232"},{"key":"e_1_2_1_7_1","first-page":"11","volume-title":"Microbial contamination of enteral liquid nutritional systems. 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IN Report of the Ross Workshop on Contamination of Enteral Feeding Products During Clinical Usage","author":"Byrum B.","year":"1983"},{"key":"e_1_2_1_14_1","first-page":"594","article-title":"Enteral nutrient solutions (ENS)","volume":"4","author":"Furtado D.","year":"1980","journal-title":"JPEN"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/136.1.137"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/135.2.308"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9378(16)32795-8"},{"key":"e_1_2_1_18_1","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1128\/iai.13.5.1315-1320.1976","article-title":"Experimental Group B Streptococcal infections in mice: Hematogenous virulence and mucosal colonization","volume":"13","author":"Furtado D.","year":"1976","journal-title":"Infect Immun"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1139\/m81-180"},{"key":"e_1_2_1_20_1","doi-asserted-by":"crossref","first-page":"466","DOI":"10.1128\/jcm.9.4.466-470.1979","article-title":"Laboratory and field evaluation of selective media for isolation of Group B Streptococci","volume":"9","author":"Gray BM","year":"1979","journal-title":"J Clin Microbiol"},{"first-page":"40","volume-title":"Report of the Ross Workshop on Contamination of Enteral Feeding Products During Clinical Usage","year":"1983","key":"e_1_2_1_21_1"},{"key":"e_1_2_1_22_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607184008006673"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-3476(76)81127-4"},{"volume-title":"The effect of bacterial contamination of commercial enteral nutrient solutions (ENS) on gastrointestinal function and fecal microflora","author":"Foley AE","key":"e_1_2_1_24_1"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607184008005591"}],"container-title":["Journal of Parenteral and Enteral Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0148607186010005503","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T17:55:27Z","timestamp":1760637327000},"score":1,"resource":{"primary":{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0148607186010005503"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,9]]},"references-count":24,"journal-issue":{"issue":"5","published-print":{"date-parts":[[1986,9]]}},"alternative-id":["10.1177\/0148607186010005503"],"URL":"https:\/\/doi.org\/10.1177\/0148607186010005503","archive":["Portico"],"relation":{},"ISSN":["0148-6071","1941-2444"],"issn-type":[{"type":"print","value":"0148-6071"},{"type":"electronic","value":"1941-2444"}],"subject":[],"published":{"date-parts":[[1986,9]]}}}