{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T21:40:40Z","timestamp":1773956440181,"version":"3.50.1"},"reference-count":17,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1986,11,1]],"date-time":"1986-11-01T00:00:00Z","timestamp":531187200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[1986,11]]},"abstract":"<jats:p>The relationship between nutritional state and wound healing was examined in 66 adult surgical patients. Wound\u2010healing response was assessed by measuring the collagen content (hydroxyproline) of fine tubes of Gore\u2010tex inserted subcutaneously along standardized needle track arm wounds. After a period of 7 days, the tubes were removed and it was found that there was a higher hydroxyproline content in the tubing of 36 normally nourished patients than there was in the tubing of 21 patients with mild protein energy malnutrition <jats:italic>(p<\/jats:italic> &lt; 0.01) and 9 patients with moderate to severe protein energy malnutrition (p &lt; 0.01). There was no difference in the wound\u2010healing response between the two latter groups of patients who had significantly different degrees of malnutrition. The results suggest that a definite abnormality in the wound\u2010healing response exists in malnourished surgical patients, but it occurs earlier in the course of the illness than previously supposed. <jats:italic>(Journal of Parenteral and Enteral Nutrition<\/jats:italic> 10:550\u2013554, 1986)<\/jats:p>","DOI":"10.1177\/0148607186010006550","type":"journal-article","created":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T19:51:26Z","timestamp":1210794686000},"page":"550-554","source":"Crossref","is-referenced-by-count":192,"title":["Impaired Wound Healing in Surgical Patients with Varying Degrees of Malnutrition"],"prefix":"10.1002","volume":"10","author":[{"given":"David A.","family":"Haydock","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Graham L.","family":"Hill","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1986,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1933.01170110031002"},{"key":"e_1_2_1_3_1","first-page":"751","article-title":"The relation of protein deficiency to experimental wound healing","volume":"85","author":"Kobak MW","year":"1947","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_4_1","first-page":"639","article-title":"The effect of methionine on the production of mucopolysaccharides and collagen in healing wounds of protein\u2010depleted animals","volume":"102","author":"Udupa KN","year":"1956","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_5_1","first-page":"15","article-title":"Effects of protein depletion on strength of colonic anastomoses","volume":"134","author":"Daly JM","year":"1972","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_6_1","first-page":"33","article-title":"Effects of malnutrition and hyperalimentation on wound healing","volume":"146","author":"Irvin TT","year":"1978","journal-title":"Surg Gynecol Obstet"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-4804(82)90054-3"},{"key":"e_1_2_1_8_1","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1093\/ajcn\/32.7.1527","article-title":"Assessment of protein nutrition in surgical patients: The value of anthropometrics","volume":"32","author":"Collins JP","year":"1979","journal-title":"Am J Clin Nutr"},{"key":"e_1_2_1_9_1","volume-title":"New Zealanders and their diet. A report to the National Heart Foundation of New Zealand on the National Dietary Survey","author":"Birkbeck JA","year":"1977"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.21.3.359"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(69)90075-8"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(67)90167-2"},{"key":"e_1_2_1_13_1","first-page":"22","volume-title":"Handbook of total parenteral nutrition","author":"Grant JP","year":"1980"},{"key":"e_1_2_1_14_1","first-page":"187","article-title":"The tensile strength of healing wounds and collagen formation in rats and rabbits","volume":"126","author":"Sandberg N.","year":"1963","journal-title":"Acta Chir Scand"},{"key":"e_1_2_1_15_1","first-page":"333","article-title":"Biochemical basis of tensile strength in wound healing","author":"Viljanto J.","year":"1964","journal-title":"Acta Chir Scand"},{"key":"e_1_2_1_16_1","first-page":"863","article-title":"The assessment of the functional aspects of malnutrition","volume":"153","author":"Russel DM","year":"1983","journal-title":"Commonwealth Agricultural Bureau"},{"key":"e_1_2_1_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800710732"},{"key":"e_1_2_1_18_1","first-page":"109","volume-title":"Wound healing: IN Current Surgical Diagnosis and Treatment","author":"Hunt TK","year":"1983"}],"container-title":["Journal of Parenteral and Enteral Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0148607186010006550","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T17:21:20Z","timestamp":1760635280000},"score":1,"resource":{"primary":{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0148607186010006550"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1986,11]]},"references-count":17,"journal-issue":{"issue":"6","published-print":{"date-parts":[[1986,11]]}},"alternative-id":["10.1177\/0148607186010006550"],"URL":"https:\/\/doi.org\/10.1177\/0148607186010006550","archive":["Portico"],"relation":{},"ISSN":["0148-6071","1941-2444"],"issn-type":[{"value":"0148-6071","type":"print"},{"value":"1941-2444","type":"electronic"}],"subject":[],"published":{"date-parts":[[1986,11]]}}}