{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T15:36:47Z","timestamp":1760888207964,"version":"build-2065373602"},"reference-count":25,"publisher":"Wiley","issue":"5","license":[{"start":{"date-parts":[[1987,9,1]],"date-time":"1987-09-01T00:00:00Z","timestamp":557452800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[1987,9]]},"abstract":"<jats:p>Ambulatory total parenteral nutrition (TPN) at home was used in 85 patients within a 6\u2010yr period Indications include severe malabsorption, fistulas, anorexia nervosa, and malignancies. The median duration of home TPN (HPN) was 67 days (range: 30\u20134,155 days). HPN duration for patients with benign diseases was longer [357.12 days (range: 30\u20134,155 days)] than for cancer patients [93.54 days (range: 30\u2013421 days)]. Under HPN, patients gained a good nutritional status with an increase of total protein (<jats:italic>p<\/jats:italic> &gt; 0.001) and serum albumin levels (<jats:italic>p<\/jats:italic> &gt; 0.001). Weight gain was also significant (<jats:italic>p<\/jats:italic> &gt; 0.001). The rehospitalization rate was low (7.8%), but it was higher when HPN lasted for more than 3 months (10.87% \u00b1 1.58%) compared with short\u2010term HPN (5.69% \u00b1 1.25%). Metabolic complications were unusual, and rehospitalization was related to the oncological treatment and\/or infectious complications. Therefore, ambulatory HPN is a nutritional support that can significantly improve the life of patients with alimentary failure. Moreover, HPN allows significant cost savings compared to the alternative of prolonged hospitalization. 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