{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,19]],"date-time":"2026-01-19T02:59:11Z","timestamp":1768791551582,"version":"3.49.0"},"reference-count":26,"publisher":"Wiley","issue":"6","license":[{"start":{"date-parts":[[1991,11,1]],"date-time":"1991-11-01T00:00:00Z","timestamp":688953600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[1991,11]]},"abstract":"<jats:p>Fatty infiltration of the liver with cholestasis is one of the complications of total parenteral nutrition (TPN). The cause has not yet been determined. It seems probable, however, that these alterations could be prevented when a mixture of medium\u2010 and long\u2010chain triglycerides (MCT\/LCT) is used as a fat component instead of the application of long\u2010chain emulsions (LCT) alone. To determine whether this could also be demonstrated morphologically in man, 14 patients needing TPN (25 kcal\/kg BW x day, carbohydrate 45%, fat 35%, protein 20%) were examined by ultrasound in order to compare liver size and gray\u2010scale value before and after 7 days of TPN. Seven of the patients were randomly administered a MCT\/LCT emulsion as their fat intake, the other seven were exclusively given LCT. There were no changes in liver size and gray\u2010scale value in the MCT\/LCT\u2010group, whereas both parameters showed a significant rise in the patients with LCT (size: 10.4 \u00b1 1.4 to 11.5 \u00b1 1.4 cm; gray\u2010scale value: 9.3 \u00b1 1.0 to 11.6 \u00b1 0.7). These data suggest that TPN, administered with a mixture of MCT\/LCT emulsions as fat components, could reduce the risk of hepatic dysfunction such as cholestasis and fatty infiltration of the liver. 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Ultrasound"],"prefix":"10.1002","volume":"15","author":[{"given":"H.","family":"Baldermann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Wicklmayr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Rett","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Banholzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Dietze","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Mehnert","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1991,11]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(76)90088-X"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607186010002172"},{"key":"e_1_2_1_4_1","first-page":"332","article-title":"Cholestatic 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