{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T22:17:16Z","timestamp":1769811436273,"version":"3.49.0"},"reference-count":21,"publisher":"Wiley","issue":"3","license":[{"start":{"date-parts":[[1993,5,1]],"date-time":"1993-05-01T00:00:00Z","timestamp":736214400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[1993,5]]},"abstract":"<jats:p>An economic analysis accompanied a multicenter Department of Veterans Affairs randomized, controlled trial of perioperative total parenteral nutrition (TPN). The cost of providing TPN for an average of 16.15 days before and after surgery was $2405, more than half of which ($1025) included costs of purchasing, preparing, and delivering the TPN solution itself; lipid solutions accounted for another $181, additional nursing care for $843, and miscellaneous costs for $356. Prolonged hospital stay added another $764 per patient to the $2405 cost of providing TPN, bringing the total to $3169. The incremental costs attributed to perioperative TPN were highest ($3921) for the patients least likely to benefit, that is, those who were less malnourished and at low risk of nutrition\u2010related complications. Incremental costs were lowest ($3071) for high\u2010risk patients. On the basis of the hospital\u2010based method of administering TPN that was used in the clinical trial, perioperative TPN did not result in decreased costs for any subgroup of patients. (<jats:italic>Journal of Parenteral and Enteral Nutrition<\/jats:italic> <jats:bold>17:<\/jats:bold>201\u2013209, 1993)<\/jats:p>","DOI":"10.1177\/0148607193017003201","type":"journal-article","created":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T19:51:26Z","timestamp":1210794686000},"page":"201-209","source":"Crossref","is-referenced-by-count":40,"title":["Does Perioperative Total Parenteral Nutrition Reduce Medical Care Costs?"],"prefix":"10.1002","volume":"17","author":[{"given":"John M.","family":"Eisenberg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Henry A.","family":"Glick","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gordon P.","family":"Buzby","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bruce","family":"Kinosian","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William O.","family":"Williford","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1993,5]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199108223250801"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/014860718601000103"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607184008003245"},{"key":"e_1_2_1_5_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607184008006632"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607190014005501"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0097-5990(16)30368-2"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-107-2-195"},{"key":"e_1_2_1_9_1","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1093\/ajcn\/47.2.382","article-title":"Measuring the economic impact of perioperative total parenteral nutrition: Principles and design","volume":"47","author":"Eisenberg JM","year":"1988","journal-title":"Am J Clin Nutr"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1017\/S0266462300006413"},{"key":"e_1_2_1_11_1","first-page":"1214","article-title":"Preoperative total parenteral nutrition in upper gastrointestinal cancer: How much for how much?","volume":"84","author":"Koretz RL","year":"1983","journal-title":"Gastroenterology"},{"key":"e_1_2_1_12_1","first-page":"1376","article-title":"Achieving parenteral nutrition cost savings through prescribing guidelines and formulary restrictions","volume":"44","author":"Maswosse JJ","year":"1987","journal-title":"Am J Hosp Pharm"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0148607188012004371"},{"key":"e_1_2_1_14_1","first-page":"707","article-title":"Parenteral and enteral nutrition: A cost\u2010benefit audit","volume":"65","author":"Roberts D.","year":"1982","journal-title":"Minn Med"},{"key":"e_1_2_1_15_1","doi-asserted-by":"publisher","DOI":"10.1177\/014860718500900103"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"366","DOI":"10.1093\/ajcn\/47.2.366","article-title":"Study protocol: Randomized clinical trial of total parenteral nutrition in malnourished surgical patients. 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