{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,20]],"date-time":"2025-10-20T17:49:49Z","timestamp":1760982589114,"version":"build-2065373602"},"reference-count":15,"publisher":"Wiley","issue":"2","license":[{"start":{"date-parts":[[1994,3,1]],"date-time":"1994-03-01T00:00:00Z","timestamp":762480000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[1994,3]]},"abstract":"<jats:p>Hypophosphatemia due to parenteral nutrition has been described frequently. It was attributed to the lack of phosphorus content in parenteral nutrition solutions. With modern parenteral nutrition regimens containing phosphorus, this problem has been virtually eliminated. Enteral nutrition solutions contain adequate phosphate for patients with normal phosphate stores. Hypophosphatemia has therefore rarely been reported in enteral nutrition. We describe two patients with protein\u2010energy malnutrition who developed severe hypophosphatemia during tube feeding with phosphorus\u2010containing formula diets. Chronic alcoholism and vitamin D deficiency due to malabsorption because of Crohn's disease were additional risk factors in these two patients. Patients with depleted phosphate stores and high metabolic demand have a higher daily requirement for phosphorus than is available in routine isotonic enteral formulas. This case report emphasizes the importance of monitoring serum phosphate concentration daily during the first week of refeeding. (<jats:italic>Journal of Parenteral and Enteral Nutrition<\/jats:italic> <jats:bold>18:<\/jats:bold>182\u2013184, 1994)<\/jats:p>","DOI":"10.1177\/0148607194018002182","type":"journal-article","created":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T19:51:26Z","timestamp":1210794686000},"page":"182-184","source":"Crossref","is-referenced-by-count":22,"title":["Enteral Supplementation of Phosphate Does Not Prevent Hypophosphatemia During Refeeding of Cachectic Patients"],"prefix":"10.1002","volume":"18","author":[{"given":"Theresia","family":"Maier\u2010Dobersberger","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Herbert","family":"Lochs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[1994,3]]},"reference":[{"doi-asserted-by":"publisher","key":"e_1_2_1_2_1","DOI":"10.1056\/NEJM198508153130711"},{"doi-asserted-by":"publisher","key":"e_1_2_1_3_1","DOI":"10.1177\/014860719001400190"},{"doi-asserted-by":"publisher","key":"e_1_2_1_4_1","DOI":"10.1136\/bmj.295.6596.490"},{"key":"e_1_2_1_5_1","doi-asserted-by":"crossref","first-page":"393","DOI":"10.1093\/ajcn\/34.3.393","article-title":"Death resulting from overzealous total parenteral nutrition: The refeeding syndrome revisited","volume":"34","author":"Weinsier RL","year":"1981","journal-title":"Am J Clin Nutr"},{"key":"e_1_2_1_6_1","first-page":"109","article-title":"Prevention of hypophosphatemia during postoperative routine glucose administration","volume":"146","author":"Hessov I.","year":"1980","journal-title":"Acta Chir Scand"},{"key":"e_1_2_1_7_1","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0016-5085(72)80032-5","article-title":"Jr: Paresthesias, weakness, seizures and hypophosphatemia in patients receiving hyperalimentation","volume":"62","author":"Silvis SE","year":"1972","journal-title":"Gastroenterology"},{"doi-asserted-by":"publisher","key":"e_1_2_1_8_1","DOI":"10.1056\/NEJM195404012501302"},{"key":"e_1_2_1_9_1","first-page":"365","article-title":"Severe hypophosphatemia in hospitalized patients","volume":"16","author":"Camp MA","year":"1990","journal-title":"Miner Electrolyte Metab"},{"key":"e_1_2_1_10_1","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1001\/archinte.1988.00380010155016","article-title":"Severe hypophosphatemia in hospitalized patients","volume":"148","author":"Halevy J.","year":"1988","journal-title":"Arch Intern Med"},{"key":"e_1_2_1_11_1","first-page":"67","article-title":"Acute respiratory failure in association with hypophosphatemia after refeeding in anorexia nervosa","volume":"3","author":"Payne\u2010James JJ","year":"1988","journal-title":"J Clin Nutr Gastroenterol"},{"key":"e_1_2_1_12_1","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1001\/archinte.1977.03630140051013","article-title":"The pathophysiology and clinical characteristics of severe hypophosphatemia","volume":"137","author":"Knochel JP","year":"1977","journal-title":"Arch Intern Med"},{"key":"e_1_2_1_13_1","first-page":"215","article-title":"Hypophosphatemia and neurological changes secondary to oral caloric intake: A variant of hyperalimentation syndrome","volume":"73","author":"Silvis SE","year":"1980","journal-title":"Am J Gastroenterol"},{"doi-asserted-by":"publisher","key":"e_1_2_1_14_1","DOI":"10.1016\/0016-5085(91)90223-8"},{"doi-asserted-by":"publisher","key":"e_1_2_1_15_1","DOI":"10.1016\/0016-5085(89)90757-9"},{"key":"e_1_2_1_16_1","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1093\/ajcn\/55.4.873","article-title":"Phosphate transport by plasma membranes of enterocytes during development: Role of 1,25\u2010dihydroxycholecalciferol","volume":"55","author":"Ghishan FK","year":"1992","journal-title":"Am J Clin Nutr"}],"container-title":["Journal of Parenteral and Enteral Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/0148607194018002182","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T18:47:23Z","timestamp":1760640443000},"score":1,"resource":{"primary":{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/10.1177\/0148607194018002182"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1994,3]]},"references-count":15,"journal-issue":{"issue":"2","published-print":{"date-parts":[[1994,3]]}},"alternative-id":["10.1177\/0148607194018002182"],"URL":"https:\/\/doi.org\/10.1177\/0148607194018002182","archive":["Portico"],"relation":{},"ISSN":["0148-6071","1941-2444"],"issn-type":[{"type":"print","value":"0148-6071"},{"type":"electronic","value":"1941-2444"}],"subject":[],"published":{"date-parts":[[1994,3]]}}}