{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T16:13:28Z","timestamp":1783786408327,"version":"3.55.0"},"reference-count":24,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[1996,1,1]],"date-time":"1996-01-01T00:00:00Z","timestamp":820454400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["J Parenter Enteral Nutr"],"published-print":{"date-parts":[[1996,1]]},"abstract":"<jats:p><jats:italic>Background:<\/jats:italic> This two\u2010part study initially evaluated complications associated with catheters inserted via upper extremity veins. The second prospective phase compared thrombotic risk of peripheral catheter tips <jats:italic>vs<\/jats:italic> a central vein terminus. <jats:italic>Methods:<\/jats:italic> Patients from public institutions with infectious diseases were observed throughout their inpatient and outpatient use of IV catheters. Seventy\u2010two and 39 patients enrolled in phase 1 and phase 2, respectively. Phase 1 consisted of prospective observations and analysis of complications and associated risk factors. Phase 2 randomized patients to a catheter tip location in the superior vena cava or the axillosubclavian\u2010innominate vein and compared the incidence of thrombosis, phlebitis, and infection. <jats:italic>Results:<\/jats:italic> In phase 1, there was an increased risk of thrombosis with peripheral tip localization (61% <jats:italic>vs<\/jats:italic> 16%, <jats:italic>p<\/jats:italic> &lt;.05). Phase 2 confirmed increased thrombosis with tips in the axillosubclavian\u2010innominate vein compared with the superior vena cava (60% <jats:italic>vs<\/jats:italic> 21%, <jats:italic>p<\/jats:italic> &lt;.05) with an improved survival for central tip catheters (p &lt;.02). Catheters associated with thrombosis were more likely to become infected (r = 0.48, <jats:italic>p<\/jats:italic> &lt;.02). <jats:italic>Conclusions:<\/jats:italic> The experience supports use of the long arm catheter as an effective device for parenteral therapy. A novel method for placing these catheters makes most patients candidates for this approach. Placing a long arm\u2010catheter's tip in the central venous circulation reduces the risk of thrombosis. A high incidence of tip misdirection indicates a need for radiographic confirmation before use. <jats:italic>(Journal of Parenteral and Enteral Nutrition<\/jats:italic> <jats:bold>20<\/jats:bold>:20\u201324, 1996)<\/jats:p>","DOI":"10.1177\/014860719602000120","type":"journal-article","created":{"date-parts":[[2008,5,14]],"date-time":"2008-05-14T19:51:26Z","timestamp":1210794686000},"page":"20-24","source":"Crossref","is-referenced-by-count":99,"title":["Complications of Long Arm\u2010Catheters: A Randomized Trial of Central vs Peripheral Tip Location"],"prefix":"10.1002","volume":"20","author":[{"given":"Patrick J.","family":"Kearns","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Steven","family":"Coleman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John H.","family":"Wehner","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[1996,1]]},"reference":[{"key":"e_1_2_1_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-197304000-00015"},{"key":"e_1_2_1_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF03006239"},{"key":"e_1_2_1_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM196808152790702"},{"key":"e_1_2_1_5_1","first-page":"25","article-title":"Peripherally inserted central venous catheters: Low\u2010risk alternatives for ongoing venous access","volume":"160","author":"Merrell SW","year":"1994","journal-title":"West J Med"},{"key":"e_1_2_1_6_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1975.01360110190032"},{"key":"e_1_2_1_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198211000-00008"},{"key":"e_1_2_1_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197404042901401"},{"key":"e_1_2_1_9_1","doi-asserted-by":"publisher","DOI":"10.3109\/00016925309136722"},{"key":"e_1_2_1_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0003-4975(10)63290-0"},{"key":"e_1_2_1_11_1","doi-asserted-by":"publisher","DOI":"10.1378\/chest.99.2.280"},{"key":"e_1_2_1_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(91)90479-9"},{"key":"e_1_2_1_13_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1982.tb01736.x"},{"key":"e_1_2_1_14_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197706092962301"},{"key":"e_1_2_1_15_1","first-page":"144","volume-title":"Statistical Methods","author":"Snedecor GW","year":"1980"},{"key":"e_1_2_1_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/01621459.1958.10501452"},{"key":"e_1_2_1_17_1","doi-asserted-by":"crossref","first-page":"860","DOI":"10.1001\/jama.1968.03140100042009","article-title":"Growth and development of an infant receiving all nutrients exclusively by vein","volume":"203","author":"Wilmore DW","year":"1968","journal-title":"JAMA"},{"key":"e_1_2_1_18_1","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1970.01340280086023"},{"key":"e_1_2_1_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(91)90351-W"},{"key":"e_1_2_1_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197905)43:5<1937::AID-CNCR2820430554>3.0.CO;2-T"},{"key":"e_1_2_1_21_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1972.03200110035007"},{"key":"e_1_2_1_22_1","doi-asserted-by":"crossref","first-page":"1014","DOI":"10.1001\/jama.1994.03510370066034","article-title":"The relationship between the thrombotic and infectious complications of central venous catheters","volume":"271","author":"Raad II","year":"1994","journal-title":"JAMA"},{"key":"e_1_2_1_23_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-79-6-867"},{"key":"e_1_2_1_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(93)90312-D"},{"key":"e_1_2_1_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.1985.tb02259.x"}],"container-title":["Journal of Parenteral and Enteral Nutrition"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/pdf\/10.1177\/014860719602000120","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,10,16]],"date-time":"2025-10-16T15:44:01Z","timestamp":1760629441000},"score":1,"resource":{"primary":{"URL":"https:\/\/aspenjournals.onlinelibrary.wiley.com\/doi\/10.1177\/014860719602000120"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[1996,1]]},"references-count":24,"journal-issue":{"issue":"1","published-print":{"date-parts":[[1996,1]]}},"alternative-id":["10.1177\/014860719602000120"],"URL":"https:\/\/doi.org\/10.1177\/014860719602000120","archive":["Portico"],"relation":{},"ISSN":["0148-6071","1941-2444"],"issn-type":[{"value":"0148-6071","type":"print"},{"value":"1941-2444","type":"electronic"}],"subject":[],"published":{"date-parts":[[1996,1]]}}}