{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T12:33:32Z","timestamp":1793363612476,"version":"4.5.0"},"reference-count":45,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2024,11,6]],"date-time":"2024-11-06T00:00:00Z","timestamp":1730851200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"funder":[{"DOI":"10.13039\/100017950","name":"Shanghai Municipal Health Commission","doi-asserted-by":"crossref","award":["202340290"],"award-info":[{"award-number":["202340290"]}],"id":[{"id":"10.13039\/100017950","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Key Specialty Construction in Shanghai Huangpu District","award":["2023ZDZK02"],"award-info":[{"award-number":["2023ZDZK02"]}]},{"name":"Health Commission of Huangpu District, Shanghai Municipality","award":["HLM202006"],"award-info":[{"award-number":["HLM202006"]}]},{"name":"Shanghai Huangpu District Top-notch Medical Talent Program","award":["2023BJ03"],"award-info":[{"award-number":["2023BJ03"]}]},{"DOI":"10.13039\/501100001809","name":"the National Natural Science Foundation of China","doi-asserted-by":"crossref","award":["82071928"],"award-info":[{"award-number":["82071928"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Ultrason Imaging"],"published-print":{"date-parts":[[2025,3]]},"abstract":"<jats:p>\n                    To explore the image features and the diagnostic value of contrast-enhanced ultrasound (CEUS) for ductal carcinoma in situ (DCIS) of the breast. A total of 96 female patients with a solitary and histologically proven DCIS were analyzed retrospectively, and 100 female cases of invasive ductal carcinoma (IDC) lesions were used as the control group. The Breast Imaging Reporting and Data System (BI-RADS) category of breast lesions was assessed according to conventional ultrasound features. The DCIS lesions were classified into mass type and non-mass type. The CEUS characteristics of these breast lesions were retrospectively analyzed qualitatively and quantitatively. The final gold standard was biopsy or surgery with histo-pathological examination. Comparing the ultrasound images of DCIS with that of IDC, there were significant differences in echo pattern, calcification morphology, and calcification distribution (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u2009.05 for all). There was a significant difference between DCIS and IDC in enhancement intensity, perfusion defects, peripheral high enhancement, intratumoral vessels, and arrival time (AT) (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u2009.05 for all). In the logistic multivariate regression analysis, two indicators linked with DCIS were recognized: perfusion defects (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009=\u2009.002) and peripheral high enhancement (\n                    <jats:italic toggle=\"yes\">p<\/jats:italic>\n                    \u2009&lt;\u2009.001). In forecasting DCIS, the logistic regression equation resulted in an AUC of 0.689, a specificity of 0.720, and a sensitivity of 0.563. CEUS showed differences in enhancement characteristics between DCIS and IDC, with perfusion defects and peripheral high enhancement being associated with DCIS.\n                  <\/jats:p>","DOI":"10.1177\/01617346241292032","type":"journal-article","created":{"date-parts":[[2024,11,7]],"date-time":"2024-11-07T01:01:28Z","timestamp":1730941288000},"page":"59-67","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Image Features and Diagnostic Value of Contrast-Enhanced Ultrasound for Ductal Carcinoma In Situ of the Breast: Preliminary Findings"],"prefix":"10.1177","volume":"47","author":[{"given":"Weiwei","family":"Li","sequence":"first","affiliation":[{"name":"Department of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China"},{"name":"College of Health Science and Technology, Shanghai Jiaotong University School of Medicine, Shanghai, China"},{"name":"Department of Ultrasound, Ruijin Hospital Luwan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yingyan","family":"Zhao","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Ruijin Hospital Luwan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaochun","family":"Fei","sequence":"additional","affiliation":[{"name":"Department of Pathology, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ying","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Breast Surgery, Ruijin Hospital Luwan Branch, Shanghai Jiaotong University School of Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weiwei","family":"Zhan","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shujun","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China"},{"name":"College of Health Science and Technology, Shanghai Jiaotong University School of Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanyan","family":"Song","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, Shanghai Jiaotong University School of Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0964-8407","authenticated-orcid":false,"given":"Jianqiao","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of Ultrasound, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China"},{"name":"College of Health Science and Technology, Shanghai Jiaotong University School of Medicine, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2024,11,6]]},"reference":[{"key":"e_1_3_2_2_2","doi-asserted-by":"publisher","DOI":"10.3390\/jcm12052036"},{"key":"e_1_3_2_3_2","doi-asserted-by":"publisher","DOI":"10.21873\/anticanres.16305"},{"key":"e_1_3_2_4_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2023.113276"},{"key":"e_1_3_2_5_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2023.07.012"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.1007\/s10549-023-06934-y"},{"key":"e_1_3_2_7_2","doi-asserted-by":"publisher","DOI":"10.1177\/01617346221075769"},{"key":"e_1_3_2_8_2","doi-asserted-by":"crossref","unstructured":"O\u2019Keefe T Yau C Iaconetti E Jeong E Brabham C Kim P et al. Duration of endocrine treatment for DCIS impacts second events: insights from a large cohort of cases at two academic medical centers. Res Sq. 2024. https:\/\/doi.org\/10.21203\/rs.3.rs-3403438\/v1","DOI":"10.21203\/rs.3.rs-3403438\/v1"},{"key":"e_1_3_2_9_2","doi-asserted-by":"publisher","DOI":"10.3390\/healthcare11091324"},{"key":"e_1_3_2_10_2","doi-asserted-by":"publisher","DOI":"10.3390\/cancers14163905"},{"issue":"4","key":"e_1_3_2_11_2","article-title":"Predicting lymph node metastases in patients with biopsy-proven ductal carcinoma in situ of the breast: development and validation of the DCIS-met model","volume":"30","author":"Meurs CJC","year":"2023","unstructured":"Meurs CJC, van Rosmalen J, Menke-Pluijmers MBE, Siesling S, Westenend PJ. Predicting lymph node metastases in patients with biopsy-proven ductal carcinoma in situ of the breast: development and validation of the DCIS-met model. 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