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This is the first report of renal dysplasia in this breed of dog. Morphologic descriptions of the range of microscopic features observed in four cases of renal dysplasia from preclinical studies in laboratory Beagle dogs are presented (including persistent primitive mesenchyme, persistence of metanephric ducts, asynchronous differentiation of nephrons, and atypical tubular epithelium), along with a basis for the classification of the lesion.<\/jats:p>","DOI":"10.1177\/0192623310382558","type":"journal-article","created":{"date-parts":[[2010,9,30]],"date-time":"2010-09-30T22:39:35Z","timestamp":1285886375000},"page":"1051-1057","source":"Crossref","is-referenced-by-count":13,"title":["Renal Dysplasia in Beagle Dogs"],"prefix":"10.1177","volume":"38","author":[{"given":"Marc C.","family":"Bruder","sequence":"first","affiliation":[{"name":"Pfizer Ltd., IPC 330, Drug Safety Research &amp; Development, Kent CT13 9NJ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed M.","family":"Shoieb","sequence":"additional","affiliation":[{"name":"Pfizer Ltd., IPC 330, Drug Safety Research &amp; Development, Kent CT13 9NJ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Norimitsu","family":"Shirai","sequence":"additional","affiliation":[{"name":"Pfizer Inc., DSRD, Groton, Connecticut, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Germaine G.","family":"Boucher","sequence":"additional","affiliation":[{"name":"Pfizer Inc., DSRD, Groton, Connecticut, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas A.","family":"Brodie","sequence":"additional","affiliation":[{"name":"Pfizer Ltd., IPC 330, Drug Safety Research &amp; Development, Kent CT13 9NJ, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2010,9,30]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748-5827.2002.tb00007.x"},{"key":"e_1_3_2_3_1","doi-asserted-by":"crossref","unstructured":"Greaves P. 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