{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T17:03:04Z","timestamp":1777914184701,"version":"3.51.4"},"reference-count":3,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T00:00:00Z","timestamp":1762387200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Toxicol Pathol"],"published-print":{"date-parts":[[2026,2]]},"abstract":"<jats:p>The nomenclature for the female reproductive system was originally published in 2014. After 10 years of practical use, the scientific community requested from the organ working group (OWG) a review of the terminology and criteria for diagnosing ovarian sex cord\/stromal lesions. As a result, OWG proposes the use of \u201csex cord\/stromal\u201d as the base terminology for hyperplasia and tumors to better reflect their origin from the sex cord\/stroma and make the terminology internally consistent. When no predominant cell type is present, these lesions should then be designated as mixed cell type (e.g., \u201chyperplasia, sex cord\/stromal, mixed,\u201d or \u201ctumor, sex cord\/stromal, mixed, benign\u201d). When a clear, predominate cell type is present, the diagnosis should indicate that cell type (e.g., \u201csex cord\/stromal, granulosa cell\u201d or \u201csex cord\/stromal, theca cell\u201d). In the case of tumors, benign or malignant would be applied as appropriate. With these diagnostic revisions, the OWG for the female reproductive system attempts to provide clarification and refinement of criteria to be used for sex cord\/stromal lesions.<\/jats:p>","DOI":"10.1177\/01926233251375986","type":"journal-article","created":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T05:08:08Z","timestamp":1762492088000},"page":"132-148","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":1,"title":["Nonproliferative and Proliferative Lesions of the Rat and Mouse Female Reproductive System: Revised INHAND Terms for Ovarian Sex Cord\/Stromal Lesions"],"prefix":"10.1177","volume":"54","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2523-1943","authenticated-orcid":false,"given":"Ute","family":"Bach (chair)","sequence":"first","affiliation":[{"name":"Bayer AG, Wuppertal, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5390-0633","authenticated-orcid":false,"given":"Heike A.","family":"Marxfeld","sequence":"additional","affiliation":[{"name":"BASF SE, Ludwigshafen, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1867-5490","authenticated-orcid":false,"given":"Justin D.","family":"Vidal","sequence":"additional","affiliation":[{"name":"Charles River Laboratories, Ashland, Ohio, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roger","family":"Alison","sequence":"additional","affiliation":[{"name":"Roger Alison Lt., Lampeter, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7054-8544","authenticated-orcid":false,"given":"Karyn","family":"Colman","sequence":"additional","affiliation":[{"name":"Biomedical Research, Novartis, Cambridge, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0008-9809-4020","authenticated-orcid":false,"given":"Eric","family":"van Esch","sequence":"additional","affiliation":[{"name":"InSight Pathology BV, Oss, The Netherlands"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5774-9317","authenticated-orcid":false,"given":"Kyathanahalli S.","family":"Janardhan","sequence":"additional","affiliation":[{"name":"Merck &amp; Co., Inc., Rahway, New Jersey, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karen","family":"Regan","sequence":"additional","affiliation":[{"name":"Regan Path\/Tox Services, Inc, Kewadin, Michigan, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junko","family":"Satou","sequence":"additional","affiliation":[{"name":"Mediford Corporation, Shimizu-cho, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lindsay","family":"Tomlinson","sequence":"additional","affiliation":[{"name":"Alnylam Pharmaceuticals, Cambridge, Massachusetts, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7001-2985","authenticated-orcid":false,"given":"Darlene","family":"Dixon (Former Chair)","sequence":"additional","affiliation":[{"name":"National Institutes of Health, Research Triangle Park, North Carolina, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2025,11,6]]},"reference":[{"key":"e_1_3_3_2_2","doi-asserted-by":"publisher","DOI":"10.1293\/tox.27.1S"},{"key":"e_1_3_3_3_2","doi-asserted-by":"publisher","DOI":"10.1177\/0192623312438738"},{"key":"e_1_3_3_4_2","volume-title":"Paper presented at 42nd STP Annual Symposium","author":"Marxfeld H","year":"2023","unstructured":"Marxfeld H, Bach U, Vidal J, et al. INHAND: nonproliferative\/proliferative lesions of the rat and mouse female reproductive system. Paper presented at 42nd STP Annual Symposium; June 2023; Summerlin, NV."}],"container-title":["Toxicologic Pathology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01926233251375986","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.1177\/01926233251375986","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.1177\/01926233251375986","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T16:44:03Z","timestamp":1777653843000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.1177\/01926233251375986"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,11,6]]},"references-count":3,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,2]]}},"alternative-id":["10.1177\/01926233251375986"],"URL":"https:\/\/doi.org\/10.1177\/01926233251375986","relation":{},"ISSN":["0192-6233","1533-1601"],"issn-type":[{"value":"0192-6233","type":"print"},{"value":"1533-1601","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,11,6]]}}}