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The peripheral blood smear revealed that the large granules in the cytoplasm of the tumor cells were stained basophilic with Giemsa, suggesting a basophil or mast cell origin. However, these granules did not show metachromasia with toluidine blue and were stained blue to dark blue with phosphotungstic acid hematoxylin. Cellular morphology and characteristics in the specific stains of tumor cells suggested the development of a tumor of globule leukocytes in a F344Du\/Crj rat.<\/jats:p>","DOI":"10.1177\/019262339902700210","type":"journal-article","created":{"date-parts":[[2008,2,8]],"date-time":"2008-02-08T19:38:42Z","timestamp":1202499522000},"page":"233-236","source":"Crossref","is-referenced-by-count":5,"title":["Eosinophilic Granulated Cells Comprising a Tumor in a Fischer Rat"],"prefix":"10.1177","volume":"27","author":[{"given":"Rumiko","family":"Miyajima","sequence":"first","affiliation":[{"name":"Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masayo","family":"Hosoi","sequence":"additional","affiliation":[{"name":"Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shinji","family":"Yamamoto","sequence":"additional","affiliation":[{"name":"Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shin-Ichi","family":"Mikami","sequence":"additional","affiliation":[{"name":"Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Seiki","family":"Yamakawa","sequence":"additional","affiliation":[{"name":"Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hijiri","family":"Iwata","sequence":"additional","affiliation":[{"name":"Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Makoto","family":"Enomoto","sequence":"additional","affiliation":[{"name":"Biosafety Research Center, Foods, Drugs and Pesticides (An-Pyo Center), Shizuoka, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1999,3,1]]},"reference":[{"key":"atypb1","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1092120207"},{"key":"atypb2","doi-asserted-by":"publisher","DOI":"10.1016\/0021-9975(72)90012-6"},{"key":"atypb3","doi-asserted-by":"publisher","DOI":"10.1177\/030098588602300215"},{"key":"atypb4","doi-asserted-by":"publisher","DOI":"10.1177\/030098588602300309"},{"key":"atypb5","doi-asserted-by":"publisher","DOI":"10.1177\/030098589703400210"},{"key":"atypb6","doi-asserted-by":"publisher","DOI":"10.1002\/ar.1091560408"},{"key":"atypb7","first-page":"1750","volume":"42","author":"Lavy DA","year":"1983","journal-title":"Fed. 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