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The study purpose was to describe spirituality and religiosity, among persons enrolled in methadone maintenance therapy and to examine associations between spirituality, religiosity, anxiety, depression, and drug-use consequences. Using a descriptive and cross-sectional correlational design, 108 participants completed questionnaires assessing the study variables. Spiritual well-being was similar to other addiction samples and lower than healthy person samples. Most participants described themselves as spiritual or religious though religious participation was lower than in their past. The analysis indicated that spirituality, religiosity, depression, anxiety, and negative drug-use consequences are interrelated in the person with addiction. Higher anxiety was predictive of negative drug-use consequences.<\/jats:p>","DOI":"10.1177\/0193945913479452","type":"journal-article","created":{"date-parts":[[2013,2,28]],"date-time":"2013-02-28T19:50:37Z","timestamp":1362081037000},"page":"795-814","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":11,"title":["Spirituality, Religiosity, Depression, Anxiety, and Drug-Use Consequences During Methadone Maintenance Therapy"],"prefix":"10.1177","volume":"35","author":[{"given":"Linda B.","family":"Piacentine","sequence":"first","affiliation":[{"name":"Marquette University College of Nursing, Milwaukee, WI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2013,2,27]]},"reference":[{"key":"bibr1-0193945913479452","volume-title":"Diagnostic and statistical manual of mental disorders","author":"American Psychiatric Association","year":"1994","edition":"4"},{"key":"bibr2-0193945913479452","doi-asserted-by":"publisher","DOI":"10.3109\/00952999309001623"},{"key":"bibr3-0193945913479452","doi-asserted-by":"publisher","DOI":"10.1177\/0095798400026004008"},{"key":"bibr4-0193945913479452","doi-asserted-by":"publisher","DOI":"10.1177\/009164719101900106"},{"key":"bibr5-0193945913479452","volume-title":"Medication-assisted treatment for opioid addiction in opioid treatment programs. 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