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This integrative review synthesized scientific literature of informal caregiving experiences for patients with diabetic extremity wounds. Five databases were searched for relevant English-language quantitative or qualitative research; ten studies were included in the final analysis. The caregiving experience included disrupted routines, frustration, guilt, poor health care communication, helplessness, and anxiety. Increased caregiver burden and decreased quality of life were associated with higher patient amputation level, worsening wound appearance and patient pain, poor health care communication, lack of social support and\/or caregiving help, and lack of caregiver employment outside the home. Future research opportunities include further exploration of caregiver tasks and priorities, caregiving experiences in settings lacking family support structures and equitable health system access, and relationships between the caregiver experience and patient health system utilization.<\/jats:p>","DOI":"10.1177\/01939459221115694","type":"journal-article","created":{"date-parts":[[2022,8,3]],"date-time":"2022-08-03T01:53:15Z","timestamp":1659491595000},"page":"272-281","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":9,"title":["Informal Family Caregiving of Patients with Diabetic Extremity Wounds: An Integrative Review"],"prefix":"10.1177","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-4930-7479","authenticated-orcid":false,"given":"Elizabeth R.","family":"Doss","sequence":"first","affiliation":[{"name":"University of Missouri-Columbia, Columbia, MO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lori L.","family":"Popejoy","sequence":"additional","affiliation":[{"name":"University of Missouri-Columbia, Columbia, MO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2022,8,2]]},"reference":[{"key":"bibr1-01939459221115694","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2014.304"},{"key":"bibr2-01939459221115694","doi-asserted-by":"publisher","DOI":"10.2337\/dci18-0007"},{"key":"bibr3-01939459221115694","doi-asserted-by":"publisher","DOI":"10.1002\/dmrr.834"},{"key":"bibr4-01939459221115694","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1615439"},{"key":"bibr5-01939459221115694","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvn.2016.06.001"},{"issue":"12","key":"bibr6-01939459221115694","first-page":"350","volume":"32","author":"Bolton L.","year":"2020","journal-title":"Wounds"},{"key":"bibr7-01939459221115694","doi-asserted-by":"publisher","DOI":"10.1023\/A:1008836325782"},{"key":"bibr8-01939459221115694","doi-asserted-by":"publisher","DOI":"10.1016\/j.foot.2019.01.004"},{"key":"bibr9-01939459221115694","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.13342"},{"key":"bibr10-01939459221115694","unstructured":"Centers for Disease Control and Prevention. 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