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Nurses ( N\u2009=\u200930) compared their health prior to and during the first pandemic wave (March\u2013May 2020). Interviews were analyzed thematically; descriptive statistics and t-tests compared pre-pandemic to current SF-12 scores. Qualitative findings demonstrated an impact on nurses\u2019 mental health expressed as isolation, loss, intense emotions, and feelings of being expendable. Impact on nurses\u2019 physical health included exhaustion, personal protective equipment skin breakdown, limited breaks from work, and virus exposure. Quantitative results show nurses\u2019 experienced declines in overall mental health ( p\u2009&lt;\u2009.001), and multiple physical health domains: role limitations due to physical problems ( p\u2009&lt;\u2009.0001), bodily pain ( p\u2009&lt;\u2009.0001), and general health ( p\u2009&lt;\u2009.0001). Promotion of nurses\u2019 well-being and safety, as well as education in emergency preparedness, must be given precedence to protect nurses\u2019 health.<\/jats:p>","DOI":"10.1177\/01939459221148825","type":"journal-article","created":{"date-parts":[[2023,1,10]],"date-time":"2023-01-10T06:01:58Z","timestamp":1673330518000},"page":"443-454","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":18,"title":["Health Experiences of Nurses during the COVID-19 Pandemic: A Mixed Methods Study"],"prefix":"10.1177","volume":"45","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5430-7890","authenticated-orcid":false,"given":"Melissa L.","family":"Harris","sequence":"first","affiliation":[{"name":"Center of Innovation to Accelerate Discovery and Practice Transformation (ADAPT), Durham VA Health Care System, Durham, NC, USA"},{"name":"Clinical and Translational Science Institute, Duke University, Durham, NC, USA"},{"name":"University of Michigan School of Nursing, Ann Arbor, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anne","family":"McLeod","sequence":"additional","affiliation":[{"name":"University of Michigan School of Nursing, Ann Arbor, MI, USA"},{"name":"University of Michigan, Michigan Medicine, Transplant Center, Ann Arbor, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marita G.","family":"Titler","sequence":"additional","affiliation":[{"name":"University of Michigan School of Nursing, Ann Arbor, MI, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2023,1,10]]},"reference":[{"key":"bibr1-01939459221148825","doi-asserted-by":"publisher","DOI":"10.4236\/ojn.2020.1010066"},{"key":"bibr2-01939459221148825","doi-asserted-by":"publisher","DOI":"10.1891\/1061-3749.27.1.77"},{"key":"bibr3-01939459221148825","unstructured":"American Nurses Foundation. 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